ID   A0A3B5AAC8_9TELE        Unreviewed;      1049 AA.
AC   A0A3B5AAC8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Pleckstrin homology domain containing A6 {ECO:0000313|Ensembl:ENSSPAP00000014864.1};
GN   Name=PLEKHA6 {ECO:0000313|Ensembl:ENSSPAP00000014864.1};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000014864.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000014864.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B5AAC8; -.
DR   Ensembl; ENSSPAT00000015106.1; ENSSPAP00000014864.1; ENSSPAG00000011181.1.
DR   GeneTree; ENSGT00940000159692; -.
DR   Proteomes; UP000261400; Unplaced.
DR   CDD; cd13248; PH_PEPP1_2_3; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR040392; PKHA4-7_PH.
DR   PANTHER; PTHR12752; PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN; 1.
DR   PANTHER; PTHR12752:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          57..156
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          19..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          450..489
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          703..759
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          772..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          839..867
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1014..1049
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          583..641
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        19..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..225
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..288
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..472
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        801..817
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        839..855
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1049 AA;  117485 MW;  71D8CDC381782A6E CRC64;
     MNGKVNTADE ILHSQSASMV SNLSPEAQSH TRTARTPRKA AMFGKRSNSM RRNPKAEVSK
     QGWLYKQASS GVKQWSKRWF VLTDRCLFYY KDEKEDTVLG SLPLLSFRIG GVRSSDSITR
     KFAFKAEHAG TRTYYFSADS HEEQEEWIRA MSEAAEVHNQ STQRTNLDTT ADHIMVTKAP
     DSRTQQHPHA QNHNETDSDL SPHPKTNGLD SLETPPLSTT CSDLEGKIND GREREGAAIS
     GAEVGGPGPD HASHPNHHPN GWSNYGPPNT VTHNSNSKLP LSRNHSGHRA TQGHVEAGVA
     PSQNHREQQE NVILRRGFVP RTAPEKVAQR KSSMAQLQQW VNQRRGMASQ EDINSPSCYY
     PVNRGVLADY CGYSGGPQYV DEYPLYPPGV RPDSICSVSA VGGYDRRWTV EEKRRSLRDG
     FHPLYGPQIP HDPWGSQYYG GMETSMRRLS IQPRSRSVPR SPSSSSGGPY SPVPPNFVSP
     ARSPSTRFDR FPGRMREDVI YADPSVYSLR RSLSSPKYDY PGDRRSLSQG LYHHNYPVSP
     SIRNKMVPPF HDVYSRELHP TLKLNEIETS KLLGRLCEQN QILKDHETVV HRLRMDKDNL
     EESLVATHQE MELYHNQPLI IEKLQFKKET QQNQLINIRG ELSQASSALT TTRMEFEALE
     DEANAIHGDL WEQLNAGGQS ELVRRHIQKE FWRVQDVLEG LHKSNSSRGT DTAKHRVASG
     ASGSFSTNSP ASPLSSVSLT SPLSPFSPVP GCQASPNKQL GVESKFGEQN NNSEMQEVQD
     RQSANKVGIV PPRTKSPTDK LHRSSAGVFQ PNESRPNGIS RERPKSAVFP AEIKSKMTVE
     EQNERIRRNQ SSSVRDKRRS LNLSSSQTPA NYKVVRRRLT AHEIDIKDLE AAVRGQGQES
     PQEEIARLRR LQVEPEHYDI NKELMAPDKV LIPERYQDLE NNPSLSPEEQ KEKQKKLKRI
     KTLIAKSNLQ NMVPFLDGPV EGGAPASSQQ QLQEQEKRIE ISCTLAAEAS RRSRLLSAQC
     ASSPPTSPTS LVPTPPSADF PNSADIMQV
//