ID A0A3B5ABV4_9TELE Unreviewed; 303 AA.
AC A0A3B5ABV4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Palmitoyl-protein thioesterase 1 {ECO:0000256|ARBA:ARBA00014212};
DE EC=3.1.2.22 {ECO:0000256|ARBA:ARBA00012423};
DE AltName: Full=Palmitoyl-protein hydrolase 1 {ECO:0000256|ARBA:ARBA00031934};
GN Name=ppt1 {ECO:0000313|RefSeq:XP_008299740.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000018953.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000018953.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008299740.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + S-hexadecanoyl-L-cysteinyl-[protein] = H(+) +
CC hexadecanoate + L-cysteinyl-[protein]; Xref=Rhea:RHEA:19233,
CC Rhea:RHEA-COMP:10131, Rhea:RHEA-COMP:11032, ChEBI:CHEBI:7896,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29950,
CC ChEBI:CHEBI:74151; EC=3.1.2.22;
CC Evidence={ECO:0000256|ARBA:ARBA00000072};
CC -!- SIMILARITY: Belongs to the palmitoyl-protein thioesterase family.
CC {ECO:0000256|ARBA:ARBA00010758}.
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DR RefSeq; XP_008299740.1; XM_008301518.1.
DR AlphaFoldDB; A0A3B5ABV4; -.
DR STRING; 144197.ENSSPAP00000018953; -.
DR Ensembl; ENSSPAT00000019241.1; ENSSPAP00000018953.1; ENSSPAG00000014289.1.
DR GeneID; 103372011; -.
DR CTD; 5538; -.
DR GeneTree; ENSGT00940000156790; -.
DR OrthoDB; 760135at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002472; Palm_thioest.
DR PANTHER; PTHR11247:SF8; PALMITOYL-PROTEIN THIOESTERASE 1; 1.
DR PANTHER; PTHR11247; PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1; 1.
DR Pfam; PF02089; Palm_thioest; 1.
DR PRINTS; PR00414; PPTHIESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..303
FT /note="Palmitoyl-protein thioesterase 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041074485"
SQ SEQUENCE 303 AA; 33765 MW; 9F77B2982CA2A6C0 CRC64;
MSAVLLCLLL AGPVLLAASR PYDDSNNGTV PLVLWHGMGD SCCNPLSMGA IKKMIEEEIS
GIYVLSLMIG KNVVQDTENG FFMDVNEQVS MVCSQLAQDP KLKGGYNAMG FSQGAQFLRA
VAQRCPSPPM KTLISVGGQH QGVYGLPRCP GETSHICDFI RKALNSGAYS DMVQKHLVQA
QYWHDPLNDD LYKKHSLFLA DVNQERVVNE TYKKNLQLLD KFVMVKFLQD SVVDPVDSEW
FGFLKTGQAK ETETLQESVL YKEDRLGLAA MDKAGKLVFL ATEGDHLQFT REWFTANLLP
YLR
//
