ID A0A3B5AG38_9TELE Unreviewed; 188 AA.
AC A0A3B5AG38;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial {ECO:0000256|ARBA:ARBA00020530, ECO:0000256|PIRNR:PIRNR009288};
DE AltName: Full=Complex I-ASHI {ECO:0000256|ARBA:ARBA00032752, ECO:0000256|PIRNR:PIRNR009288};
DE AltName: Full=NADH-ubiquinone oxidoreductase ASHI subunit {ECO:0000256|ARBA:ARBA00032699, ECO:0000256|PIRNR:PIRNR009288};
GN Name=ndufb8 {ECO:0000313|RefSeq:XP_008287044.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000020413.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000020413.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008287044.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|PIRNR:PIRNR009288}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533, ECO:0000256|PIRNR:PIRNR009288}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004298}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004298}; Matrix side
CC {ECO:0000256|ARBA:ARBA00004298}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB8 subunit family.
CC {ECO:0000256|ARBA:ARBA00008039, ECO:0000256|PIRNR:PIRNR009288}.
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DR RefSeq; XP_008287044.1; XM_008288822.1.
DR AlphaFoldDB; A0A3B5AG38; -.
DR STRING; 144197.ENSSPAP00000020413; -.
DR Ensembl; ENSSPAT00000020727.1; ENSSPAP00000020413.1; ENSSPAG00000015421.1.
DR GeneID; 103362462; -.
DR CTD; 4714; -.
DR GeneTree; ENSGT00390000000628; -.
DR OrthoDB; 2940624at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:UniProtKB-UniRule.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:UniProtKB-UniRule.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:UniProtKB-UniRule.
DR InterPro; IPR008699; NDUFB8.
DR InterPro; IPR016551; Ndufb8_metazoa.
DR PANTHER; PTHR12840:SF1; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12840; NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT; 1.
DR Pfam; PF05821; NDUF_B8; 1.
DR PIRSF; PIRSF009288; NDUB8; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|PIRNR:PIRNR009288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR009288};
KW Mitochondrion {ECO:0000256|PIRNR:PIRNR009288};
KW Mitochondrion inner membrane {ECO:0000256|PIRNR:PIRNR009288};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Respiratory chain {ECO:0000256|PIRNR:PIRNR009288};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR009288}.
SQ SEQUENCE 188 AA; 21578 MW; 79ED8EF95B2C8C52 CRC64;
MAVVGFRRWA QALSKGKGSG ISALISGSRA ASSVGKGSLP GPYPKTPEER AAAAKKYNMI
PEDYEPYPDK GEGYGDYPML PNKSQHERDP WYSWDHSDLR RNWGETMHWD FDMYTRNRVD
TSPTVVPYHS MVKDLFLFLG FMAFMFYVGY ECKSYQPVGP KQYPYNNLYL EKGGDPEKQP
EEVKNYEL
//
