ID A0A3B5AGH4_9TELE Unreviewed; 2230 AA.
AC A0A3B5AGH4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Calcineurin binding protein 1 {ECO:0000313|Ensembl:ENSSPAP00000019885.1};
DE SubName: Full=Calcineurin-binding protein cabin-1 isoform X1 {ECO:0000313|RefSeq:XP_008274913.1, ECO:0000313|RefSeq:XP_008274914.1};
GN Name=CABIN1 {ECO:0000313|Ensembl:ENSSPAP00000019885.1};
GN Synonyms=cabin1 {ECO:0000313|RefSeq:XP_008274913.1,
GN ECO:0000313|RefSeq:XP_008274914.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000019885.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000019885.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008274913.1, ECO:0000313|RefSeq:XP_008274914.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_008274913.1; XM_008276691.1.
DR RefSeq; XP_008274914.1; XM_008276692.1.
DR STRING; 144197.ENSSPAP00000019885; -.
DR Ensembl; ENSSPAT00000020184.1; ENSSPAP00000019885.1; ENSSPAG00000014893.1.
DR GeneID; 103353630; -.
DR CTD; 23523; -.
DR GeneTree; ENSGT00390000008529; -.
DR OrthoDB; 8630at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:InterPro.
DR CDD; cd13839; MEF2_binding; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR033053; Hir3/CABIN1.
DR InterPro; IPR015134; MEF2-bd.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15502; CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED; 1.
DR PANTHER; PTHR15502:SF7; CALCINEURIN-BINDING PROTEIN CABIN-1; 1.
DR Pfam; PF09047; MEF2_binding; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891}.
FT DOMAIN 2166..2200
FT /note="Calcineurin-binding protein cabin-1 MEF2-binding"
FT /evidence="ECO:0000259|Pfam:PF09047"
FT REGION 308..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1367..1390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1422..1466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1729..1864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2108..2149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2190..2230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1422..1461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1509..1524
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1774..1803
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1809..1824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1826..1864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2108..2129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2190..2215
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2216..2230
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2230 AA; 251039 MW; B8057CECA17762E1 CRC64;
MIRIAALNAA ATAADESQDP LRSTKSQTKE AQEAEAFALY HKALDLQKHD KFEESAKAYH
ELLKTPLLKE AMASDDQRVG LKHPGLMLKY STFKNLASMA ALRDDLETAM EFYLEAVMLD
STDVNMWYKI GQVAVRLVRI PLARHAFEEG LHCNPDHWPC LDNLITILYT LSDYTCCLYF
IAKALEKDHC YTKGLVLKEK IFEEQPCLKR DTMQMFMKCD MSIHYVEVEE EERKSIVEEA
LEIRRRRQAL SHCEPKPDLV LIQPIHCLSW KHVGESFLAM YRHQTTCEPP RPSLGRRIDL
SEYRDPNFLQ NLPQPTSPVS MGQTTVLSSS PSSSLPPVTF SEPVLPQCST QPQLTTSQAT
VEVTTSAPPV ATAMEVSLTD KVKKAPKRKR VVEDSGETAK RRSARVRNTK CKKEEKIDFQ
ELLFKYLPSR LKKFDPDNDD ESLSNLETQC DGKEDIQPLH GSCLPVDSVE YMESEQQDVH
KFLLNNMTNG GILDLMMLYL KAVGKKFTEE WPRGLTAVVL EVYQNWRKHS SGLPNPLLRD
CSNQHIREML AMSLACMELQ LEQWLHNKGK IAAPRRSSSG PSNDATDSEF PGQHFQGDLL
LLALGSSQRD LFEGDWLDVM VRVYWLKARF LALQGEMELA LESYDVCIGL LQSKPKNPDG
KHYTIHLPNL HVDAAISVEE IDKRLKSLER CQSLEEIQRL FEAADFESVV RLLQPTLNYG
SRSKPLEFVS SAPERPAQLM LLQNSLLKLQ EYQQCLDCSE LALNEALQQL NSASNSSPPS
KEEWVSTIGK LLDGIEVCFS KESDLLSNVP HFSSTARLAN NLIQLIDLSM TISDDPKEPY
FFSVLPWIIL YRIIKHEEAA FDCMLRQHMS VGDDEDDSDT PMLPSSLMLL NTAHEYLGRR
SLCCNSDGAL LKFYVRVLEK EFIASTKNES HPYKEELEMA LEQCFFCLYA YPSKKSKARY
LEDHSSPQVE LLWSDALFMF QYFKPKSLPE FDSYKTSTVS AELANLLRRF SGITPTSDTP
TLTMDEVAAY IEDTAEKAPC LPPGSAPAPP IINEMYYLLA DYHFKNKEQS KAIKFYMHDI
CVCPNRFDSW AGMALARASR IQDKLNSNEL KSDVPIWKHS QAVLNCFKRA LEIDSSNLSL
WIEYGTISYA LHSFASRQLK QWRNELPPEV VKQMEERRDS MLQTAFQCFQ SASRCEGDSD
EEEWLIHYML GKIAEKRKQL PVEYVHLYKK AAHYLHEEAA RYPRKIHYHN PPDLAMEALE
LHFRLSATIL KLLEADEPDL EHENLFTLLV EAATGPFARG EEKSMPSMPR TNEKEKPTSM
MDEDFNCSSV CIGNVLSSSL PSVATPGLTS PHYVATPFDH DYAKRKTLRR QQWQQQRHEE
QQADASPEFD HDYCLPRSSL WLASLNERSQ DSEVVLLSDS NSTQDAFTDP TSSQDSSHKP
VSGKASSSSS ESTTPVKDGQ PTSEDTVLHG EHAGIQTEEK VIQEVVEAVV VIVPEALAPK
VSADHCPHPL PVPVTPPKPA PSQQATPQTP ASEGKKKLEP PAEVIEVPKA LPAERADQRR
MLVEMCVRAL FLCLSRFPQH YKSLYRLAFF YTNSRTHQNL QWARDVLLGS SVPWQQLKHM
PAQGLFCERN KTNLFNGIWR IPVDEIDRPG SFASHMNRSI VLLLEVLSQL KDHDTLLKVS
FMLQRTPDQG KKYLRDVDRQ VLAKRAFFLT VKVLEDNLNS LTGVSEQLHK APAPSMGEMT
TTDTSNRPSS EDSKHAVPKK PGLTEGACAT DTGPREASQA QLTPPPPSSD KGSKVQESYS
VKVETAGSEG HKAGPEEPME LDTAHWRKPS STTDSQGNQT EAETSLSGME AQQKVTDSSR
TPELSLEELS ISSRQQQLQA SAPKVTVAAG GTDQGLLRKP NRKRKLLEDV ESGKTLLLDA
YRVWQQGQKV MTYDLGRIEK IMSETYMLIK QVDEDVALDQ AVKFCQIQLA ASAQRQSAGD
APTTPKYTKE HRDIFFPASL PTPVLLSHST CHPLSTQDGQ AKALYEPLSK LPRPQTSGFH
DQPQHRRAAG HSAAAMAFLP HTEEREEPSE GLLYRQQESH LCQQMKLASV SQGPESAAGW
FQEETATCSS TQPCPDQQQY ASSDQSKLPD PSRIRSRVPP NMPKLFIPST VTKFPPEITV
TPPTPTLLSP KGSISEETKQ RLKNVILSSQ SAATVKKDTL SQPALEVQET SSQESSLESE
SDEEDDYMDI
//
