ID A0A3B5AGJ4_9TELE Unreviewed; 485 AA.
AC A0A3B5AGJ4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ammonium transporter Rh type C {ECO:0000313|RefSeq:XP_008274096.1};
DE SubName: Full=Rh family C glycoprotein {ECO:0000313|Ensembl:ENSSPAP00000019905.1};
GN Name=RHCG {ECO:0000313|Ensembl:ENSSPAP00000019905.1};
GN Synonyms=rhcg {ECO:0000313|RefSeq:XP_008274096.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000019905.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000019905.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008274096.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Functions as an ammonia transporter. May play a role in the
CC elimination of ammonia in the gill. {ECO:0000256|ARBA:ARBA00025220}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC subfamily. {ECO:0000256|ARBA:ARBA00011036}.
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DR RefSeq; XP_008274096.1; XM_008275874.1.
DR AlphaFoldDB; A0A3B5AGJ4; -.
DR STRING; 144197.ENSSPAP00000019905; -.
DR Ensembl; ENSSPAT00000020203.1; ENSSPAP00000019905.1; ENSSPAG00000014996.1.
DR GeneID; 103353094; -.
DR CTD; 792274; -.
DR GeneTree; ENSGT00950000182844; -.
DR OrthoDB; 5483564at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR InterPro; IPR002229; RhesusRHD.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF110; AMMONIUM TRANSPORTER RH TYPE C-LIKE 2-RELATED; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR PRINTS; PR00342; RHESUSRHD.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..435
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 485 AA; 53476 MW; 3C03343CD211A558 CRC64;
MGAVQSFREM CDRPKNTNVR LSLPAVCFVW QTAMIILFGV FIRYNEEADA HWVEYKKEKN
IASDIENDFY FRYPSFQDVH VMIFVGFGFL MTFLKRYSFG AVGFNFLIAA FGLQWALLMQ
GWFHSLDYTD GKIKIGVESL INADFCVAGC LIAYGAVLGK VSPVQLMVLT LFGITLFAVE
EYIILDLIHA RDAGGSMVIH TFGGYYGLSI SWMLYRPNLD QSSRLQGSVY HSDVFAMIGT
LFLWMFWPSF NSAITDHGDG QHRAAINTYL ALASTVLTTV AISSLFQKHG KLDMVHIQNS
TLAGGVAVGT AAEFMLMPYG SLIVGFCCGI ISTLGYIYLT PFMEKYLKIQ DTCGIHNLHA
MPGVIGGIVG AITAAAASES VYGAEGLINT FDFEGEYKNM APTKQGGHQA AGLCVAICFG
VGGGILVGFI LRLPIWGDAA DDNCFDDEPY WELPEDEESV PPVLQYNNHA INKDVAESNF
TMEQN
//
