ID   A0A3B5AGM3_9TELE        Unreviewed;       535 AA.
AC   A0A3B5AGM3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Ral GEF with PH domain and SH3 binding motif 1 {ECO:0000313|Ensembl:ENSSPAP00000019561.1};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000019561.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000019561.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B5AGM3; -.
DR   STRING; 144197.ENSSPAP00000019561; -.
DR   Ensembl; ENSSPAT00000019856.1; ENSSPAP00000019561.1; ENSSPAG00000014745.1.
DR   GeneTree; ENSGT00940000154079; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd13310; PH_RalGPS1_2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR008937; Ras-like_GEF.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR23113:SF167; RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF48366; Ras GEF; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW   ECO:0000256|PROSITE-ProRule:PRU00168}.
FT   DOMAIN          29..270
FT                   /note="Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50009"
FT   DOMAIN          409..521
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          304..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  60286 MW;  9E4A0F4FA109DD4F CRC64;
     IYKGSESLIS LLFTSMFNGL SSSESLDGPC VDYAKSYDAV VFDVLKVTPE EFAELASCGW
     NGKEKHSLAP NVVAFTRRFN QVSFWLVREI LTAQTLKIRA EILSHFVKIA KKLLELNNLH
     SLVSVVSALQ SAPIFRLSKT WALVSRKDRA TFEKLNYLTS KEENYTRMRE YIRSLKMVPC
     IPYLGIYLLD MIYIDSAYPA SDSIIETEQR TNQMNNLLRV ISDLQMSCNY DYLVTLPHVQ
     KYLLSVRYIE ELQKFVEDDN FKLSLKIEPG SSSPRIASSK EDLAGLSEVS VSMRYNRRPT
     CPDASVGVHI STPPPSHHRK SHSLGNNMMC QYGMSESRSA TFPIEKARHL LDDSFLESQS
     PVRNDPHSTS VSNGLSLGIS ESSFGEELSP GMESSTATNT CYGCSDSSNV TIEGPLRRKT
     MLKEGRKPKL SSWTRFWITL SGSTLTFYGA KALRASERKH YKSSPCKKVC VTGWMVVLPD
     DPARPNIFHL NDPDKGNVYK FQTGSRFSAI IWHKNLEEAC RSSRPQIPAN LMSFE
//