ID A0A3B5AJP8_9TELE Unreviewed; 163 AA.
AC A0A3B5AJP8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Placenta growth factor {ECO:0000313|RefSeq:XP_008281495.1};
DE SubName: Full=Placental growth factor {ECO:0000313|Ensembl:ENSSPAP00000013737.1};
GN Name=pgf {ECO:0000313|RefSeq:XP_008281495.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000013737.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000013737.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008281495.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|RuleBase:RU003818}.
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DR RefSeq; XP_008281495.1; XM_008283273.1.
DR AlphaFoldDB; A0A3B5AJP8; -.
DR STRING; 144197.ENSSPAP00000013737; -.
DR Ensembl; ENSSPAT00000013967.1; ENSSPAP00000013737.1; ENSSPAG00000010402.1.
DR GeneID; 103358345; -.
DR CTD; 557468; -.
DR GeneTree; ENSGT00940000160164; -.
DR OrthoDB; 4231319at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR PANTHER; PTHR12025:SF9; PLACENTA GROWTH FACTOR; 1.
DR PANTHER; PTHR12025; VASCULAR ENDOTHELIAL GROWTH FACTOR; 1.
DR Pfam; PF00341; PDGF; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..163
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041074542"
FT DOMAIN 33..130
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
FT REGION 136..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 163 AA; 19012 MW; BD8A9A63AB54A099 CRC64;
MKVGFVIETV VALYLLLSPA QTLPLSSING TMEVLMFQEV WGRSFCRTIE KLVEVVQEYP
TEVEHIYSPS CVPLVRCAGC CGDENLECHP THTTNVTMQL LKIRPSEPGQ EYVEMTFVEH
QTCECRIRKP VVKVERKRQR TRERKRKERQ KSKECDRCQI PRR
//
