ID   A0A3B5AM36_9TELE        Unreviewed;       484 AA.
AC   A0A3B5AM36;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Ataxin-10 {ECO:0000256|ARBA:ARBA00018804};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000022548.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000022548.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Necessary for the survival of cerebellar neurons. Induces
CC       neuritogenesis by activating the Ras-MAP kinase pathway. May play a
CC       role in the maintenance of a critical intracellular glycosylation level
CC       and homeostasis. {ECO:0000256|ARBA:ARBA00002116}.
CC   -!- SIMILARITY: Belongs to the ataxin-10 family.
CC       {ECO:0000256|ARBA:ARBA00008384}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B5AM36; -.
DR   STRING; 144197.ENSSPAP00000022548; -.
DR   Ensembl; ENSSPAT00000022908.1; ENSSPAP00000022548.1; ENSSPAG00000016957.1.
DR   GeneTree; ENSGT00390000010377; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019156; Ataxin-10_domain.
DR   PANTHER; PTHR13255; ATAXIN-10; 1.
DR   PANTHER; PTHR13255:SF0; ATAXIN-10; 1.
DR   Pfam; PF09759; Atx10homo_assoc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        110..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          381..477
FT                   /note="Ataxin-10"
FT                   /evidence="ECO:0000259|Pfam:PF09759"
SQ   SEQUENCE   484 AA;  54045 MW;  D28EE687C4FB0380 CRC64;
     MAAPTDNSLQ ISASIADILN ENHQPQHLQA LKTFTTALRE KEFRDAVEEE VFSSLLKVLT
     RLCEELQAAN SDGEDLQSFT LQLQLTAECF RAQRNSCIQS TRNQTLLRDL GFIDVLSFIL
     LYLIKGLNAL FLDVDLFCFK SSSALRCGIQ FLGNLAVGNQ MCKDDIWQLS FPNLLLVEDE
     KTVNYTSMVL HTCLDEAKVE DLSNPQNIQL ALRVMELCRT QPDLDWTVII ATQHFLRSSA
     LVESMYSGMS HHERVTLLEL LFAQLREEDS EECGVPPSVA RFLASSFQQG CGAVLTLATG
     SVLQEALTVI SLLDVLCEMT SDNKQFMFLQ DHPDLLMTTV GLLEQVHAIG KASKNIFSAA
     QNFSSFGGDV DSSSHSPVIS FKAHLIRLIG NLCHGNTDNQ NKVRELEGIP LILDNCNIDS
     NNPFISQWAI FTIRNLLEHN TQNQQLVANL ERRGTADYSA LRELGFLVEE RDGSLLLKPV
     RKDS
//