ID A0A3B5AYJ6_9TELE Unreviewed; 364 AA.
AC A0A3B5AYJ6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=ALX homeobox 4 {ECO:0000313|Ensembl:ENSSPAP00000018587.1};
DE SubName: Full=Homeobox protein aristaless-like 4 {ECO:0000313|RefSeq:XP_008277142.1};
GN Name=alx4 {ECO:0000313|RefSeq:XP_008277142.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000018587.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000018587.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008277142.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR RefSeq; XP_008277142.1; XM_008278920.1.
DR AlphaFoldDB; A0A3B5AYJ6; -.
DR STRING; 144197.ENSSPAP00000018587; -.
DR Ensembl; ENSSPAT00000018868.1; ENSSPAP00000018587.1; ENSSPAG00000014031.1.
DR GeneID; 103355220; -.
DR CTD; 497424; -.
DR GeneTree; ENSGT00940000159662; -.
DR OrthoDB; 5400675at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR003654; OAR_dom.
DR PANTHER; PTHR24329; HOMEOBOX PROTEIN ARISTALESS; 1.
DR PANTHER; PTHR24329:SF322; HOMEOBOX PROTEIN ARISTALESS-LIKE 4; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF03826; OAR; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS50803; OAR; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 168..228
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 344..357
FT /note="OAR"
FT /evidence="ECO:0000259|PROSITE:PS50803"
FT DNA_BIND 170..229
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 86..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 364 AA; 39786 MW; 6B2C943F0F0D2684 CRC64;
MNADTCVSYC DMTSMDSYYS TSTAQGRDHQ ATFPTTETKY SSTFIPGKGQ AYGEKSRSPF
QPECHSLDGA EEGTFSKYQL FMQRPTCKTP PEGSKLHPDS GHNGTLIPCY GKDNSGLTES
ELPPSVNPPG MEGSYLNLKE PGVKGPSERP GSDLSSPLDK SEAESNKGKK RRNRTTFTSY
QLEELEKVFQ KTHYPDVYAR EQLALRTDLT EARVQVWFQN RRAKWRKRER FGQMQQVRTH
FSTAYELPLL TRPENYAQIQ NPSWIGSSSG ASPVPGCVVP CDSVASCMPP HPHGPGGVSD
FLGVPSPGSS HMGQTHMGSL FGGAGIGGGI NGYDLNVDPD RKSSSIAALR MKAKEHSAAI
SWAT
//
