ID A0A3B5AZA9_9TELE Unreviewed; 206 AA.
AC A0A3B5AZA9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Platelet-derived growth factor subunit A {ECO:0000256|ARBA:ARBA00040278};
DE AltName: Full=Platelet-derived growth factor A chain {ECO:0000256|ARBA:ARBA00042479};
DE AltName: Full=Platelet-derived growth factor alpha polypeptide {ECO:0000256|ARBA:ARBA00041285};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000025811.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000025811.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
CC {ECO:0000256|ARBA:ARBA00006686, ECO:0000256|RuleBase:RU003818}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B5AZA9; -.
DR Ensembl; ENSSPAT00000026235.1; ENSSPAP00000025811.1; ENSSPAG00000019485.1.
DR GeneTree; ENSGT00940000159039; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd00135; PDGF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR023581; PD_growth_factor_CS.
DR InterPro; IPR000072; PDGF/VEGF_dom.
DR InterPro; IPR006782; PDGF_N.
DR PANTHER; PTHR11633; PLATELET-DERIVED GROWTH FACTOR; 1.
DR PANTHER; PTHR11633:SF3; PLATELET-DERIVED GROWTH FACTOR SUBUNIT A; 1.
DR Pfam; PF00341; PDGF; 1.
DR Pfam; PF04692; PDGF_N; 1.
DR SMART; SM00141; PDGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00249; PDGF_1; 1.
DR PROSITE; PS50278; PDGF_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|RuleBase:RU003818};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..206
FT /note="Platelet-derived growth factor subunit A"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017273515"
FT DOMAIN 92..193
FT /note="Platelet-derived growth factor (PDGF) family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50278"
SQ SEQUENCE 206 AA; 24097 MW; DFD68F2CBD4D72F3 CRC64;
MRAALGYFLL WTTYLLLVTA EEVEFPQELI DRLSHSEIHS ISDLQRLLEI DSVGNDVIEE
AKYHKHHNHH KNYSRHHGYY NDLKSSQLHS RRKRSIVEEA VPAVCKTRTV IYEIPRSQVD
PTSANFLIWP PCVEVKRCTG CCNTSNMRCH PSRKHHRTVK VAKVEYVRRR PKLKEVFVRL
EDHLECVCTS QHHVAEHSDA ETVDVR
//
