ID A0A3B5B298_9TELE Unreviewed; 1767 AA.
AC A0A3B5B298;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Trinucleotide repeat-containing gene 6C protein-like {ECO:0000313|Ensembl:ENSSPAP00000019877.1};
GN Name=TNRC6C {ECO:0000313|Ensembl:ENSSPAP00000019877.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000019877.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000019877.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GW182 family.
CC {ECO:0000256|ARBA:ARBA00007302}.
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DR Ensembl; ENSSPAT00000020173.1; ENSSPAP00000019877.1; ENSSPAG00000014977.1.
DR GeneTree; ENSGT00940000157598; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd14283; UBA_TNR6C; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR019486; Argonaute_hook_dom.
DR InterPro; IPR026805; GW182_M_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR041917; TNR6C_UBA.
DR InterPro; IPR032226; TNRC6_PABC-bd.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR13020; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6; 1.
DR PANTHER; PTHR13020:SF9; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN; 1.
DR Pfam; PF10427; Ago_hook; 1.
DR Pfam; PF12938; M_domain; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF16608; TNRC6-PABC_bdg; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 997..1042
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 80..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1215..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1304..1395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1410..1471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1516..1547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1662..1716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 738..758
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..864
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 875..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 964..986
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1123
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1215..1243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1270..1291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1307..1338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1359..1395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1417..1471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1662..1681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1690..1712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1767 AA; 183979 MW; 9C425979AA3F3937 CRC64;
MEDKKKKKQE EKKNKEAALK KATEQITKEL PPQSGQGAQY DNPLWGHLPA NRSATNAASS
TNLSGWDQLI IDQKDTEAWP SITLSQSQAP PGGCSLDTDP GHLTSSSSSS SSSSTSSTCS
TVSMATGANS QTGHFPANHL SSKANSGPSP ANHTGTSMLS SQVATNRSWG TGPGPSHCPP
QSSGGSEGKG DSPVGGGGGG GSRGWGSSSS SSTTNFNLNL NPNANPSAWP MLGHDGGGTG
GGSSGGANTI SPPQPTPNLC NPTGPPPAKT STCTGANTNS NSSGIGSAWG TIMASDAPEP
HPSPSTNVSF SSEPQNLKTD GPNHTNKQEP PSPIRNLPGW GSAPVGLGSM SQPPTGASQV
NGEDGNSVWG NSGNSKATPS KEAPGWDSGW GHGGGGAGNS GGWGEQSGGD WGKQHTEEAQ
GGWDAPSSPP QDSQASPWSR AVSTAGASEG SSDSMEGHPQ RRDRSSRDNP APLLPAQDLD
PRVLCNTGWG QTPVRQHTSW DMDNTKRKND AGTESWGSGP TTPSDAQGPS NTGPTQRTDS
GSKNDVPGSQ GASGWGGSIA ATNQSSSGWG ETSNNIKPPG GPGGWGNPPA GGPNTNIPKN
GGQSWGEEKS AGWEDSHIKS TSQSWGEQPK ASHNWGNSGG SNNAGDWGEP EDSKKSPSNP
GWEGEAGGWK ENPRGWGMSS SGPGISGAGG NGGWGESVPQ RPSGPPQGWG GKPQDGPSGN
SGGGGGGGMG SWGGSGSVKQ GAGWSGSKQD SSAEPTGWEE PSPPSIRRKM EIDDGTSAWG
DPGTYNKSVN LWDRNNPGMS QTKGTAGGNN PPGSNNNHAH SHNHPYHGPP APLQNHSQNS
QNPGPTSGPM DPPVQHQSAP SHSRGPLIAQ GWGELPSSHT KSESSWGEPA PSPVSVDNGT
SAWGKPTGSC GGWGEGNPDN YGRGNPAMTA APCKPAPKPM QDGWGGGGEE LSLSGGQWDA
EEGDMWNSTA SQESNSSCNS WGNASKKGPQ KGKVPGKQED TWIMNRLVKQ LTDMGFPRDP
AEEALKSNNM NLDQAMSALL EKKTELDKRG MGMSGHDYNN GLINKPMSCP RPPLLSKDPS
ADPRLPFMDK MQSGMFGGGG AAQARAMQQP QPPPQPPVPP LSSSQPSLRA QVPQFLSPQV
QAQLLQFAAK NIGLNPALLT SPINPQHMTL LNQLYQLQLA YQRLQIQQQM LQAQRNVSGP
IRQQEQQVAR TINNMQQQIQ QHQRQLAQAL LMKQQQQQPP PSHSGLHPGG AKSSLDSFPG
HPQAPGLPDL QTKEPQSSPN TYSPYALSGL NPNMNVNCME VGSLSMKEPP QPQSRLSQWT
HPNSMESLSG NSSPLEPNLG KHGATLGPPG KPPQLDDSYS PYNLMSSSES PTSPLVPPDS
WGQGKSSSDK MANGTNINWP PEFCPGVPWK GLQNIDPETD PNVTPGSVPS GPTINTNIQD
VNRYLLRDRS GGSSPTSSQN EALPPSTDWP VSAYTSSFSL SSSEMDNAGK LSEMKSTWSP
GPISHSQASL SHELWKVPQG PRSSTTAPSR PPPGLTNTKP SSTWGGNSLG LAQGWSSSYT
TAGTTWSTDS STRTSSWLVL RNLTPQIDGS TLRTLCMQHG PLITFHLNLT QGNAVVRYSS
KDEAAKAQKS LHMCVLGNTT ILAEFAGEEE VNRFFAQGQS LGGTTSWQAS PGTNQTRMGG
AGSGASHPIG HSPHWNNNNG ASSSSSSGLG AGGTKTGGEL LWGGVQQYSS LWGPPSGEEG
RRRDGGGRRR LHLLHSFGLT TFQLQFL
//
