ID A0A3B5B2B0_9TELE Unreviewed; 969 AA.
AC A0A3B5B2B0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cingulin {ECO:0000256|ARBA:ARBA00044075};
GN Name=CGN {ECO:0000313|Ensembl:ENSSPAP00000024204.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000024204.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000024204.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Probably plays a role in the formation and regulation of the
CC tight junction (TJ) paracellular permeability barrier.
CC {ECO:0000256|ARBA:ARBA00043864}.
CC -!- SIMILARITY: Belongs to the cingulin family.
CC {ECO:0000256|ARBA:ARBA00038467}.
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DR AlphaFoldDB; A0A3B5B2B0; -.
DR STRING; 144197.ENSSPAP00000024204; -.
DR Ensembl; ENSSPAT00000024604.1; ENSSPAP00000024204.1; ENSSPAG00000018228.1.
DR GeneTree; ENSGT00940000154489; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:InterPro.
DR InterPro; IPR002928; Myosin_tail.
DR PANTHER; PTHR46349:SF4; CINGULIN; 1.
DR PANTHER; PTHR46349; CINGULIN-LIKE PROTEIN 1-RELATED; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 610..921
FT /note="Myosin tail"
FT /evidence="ECO:0000259|Pfam:PF01576"
FT REGION 23..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 925..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 280..375
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 568..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..666
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 969 AA; 111147 MW; 241C4EDD8A08E224 CRC64;
MSAPSSGRKT PVDHGVQIRF INDLHDTGGG QPGSQPKKKI HNKYGVAVRV QGIAGQPYVV
LKDGQKGDSY GVQLRTHYPS GFNSLPRSRD KPEPGTEGAD VGGGGQAGAL RRAQSHGSLL
DRDGNEDFQL SRPPGDGKSG SYGNLDAGIG VRGDREQSWP ARSRDGSMER NMWDGSYQTG
LDRSFSDLCL KVTPDLLLDQ GHSAEMSSED EEQLTQMIYN ILRQGEDTQS THTVRQKTAG
RDVVPLSVGQ FGETGSYCGL FTRQTSSSKN HSLSSCPRRL TQLRMDRENA ETRVRTMEDQ
LAELQDELRR ENGNKTVRVI LDLMSCQTQL MEVCQLKQKL EETLRQRERE LTALKGALKE
EVASHDKEIE ALREQYSVDM EKLRGSMEQV SQSHAGIEAE RLRVNASVRT LQQQLEDCRD
ESSHWMEQFH TTRDELRTQT VSVQELQRCN ADLQKTRSDL EKQRTEYDKK IMEVISIKKS
HQDQEAELKY EIDRLKDQLQ RAKDDFSKAQ EKNKRVDLNS LQDAQQEQEE ANARLKEKLS
RLEVTFHPPH SEAELALHAE VRGLRSELDE AKRKASRANQ EQRELSRRLE ESEKDKDTLK
QTVSQLEETK RQQERSLEKL TKECDSLNAS SREETQVLRV QLEEQRERAR KEMQEAQRHG
NDAQSELERT NISLRRLEEE MSRQKKELLL VCEERDNHQL DKELLTNRLR HLEGEVETGK
NSLNEKSREV RILEDKLKRL ELELEEEKSS AEMMTDRVAR SRDQIDQLRS ELMQERSSKQ
DLELDKNAME RHLKELRSRV ADMEGQSRSS AGVSQLENKV QELEDRLRAE DREKSTMLAS
QRRLERKLKD LNMTLDEERH THSEQRDQLS LRVKALKRQV DEGETELERI DGLRRKAQRD
MEEQMELKEA LQARVSALET ELKRKAQAAM RPALDSSALS SDDDDNDSLY DSSAITSILT
ESNLQTSSC
//
