ID A0A3B5B5I5_9TELE Unreviewed; 1252 AA.
AC A0A3B5B5I5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cell division cycle and apoptosis regulator 1 {ECO:0000313|Ensembl:ENSSPAP00000028420.1};
DE SubName: Full=Cell division cycle and apoptosis regulator protein 1 isoform X1 {ECO:0000313|RefSeq:XP_008302739.1, ECO:0000313|RefSeq:XP_008302740.1};
GN Name=ccar1 {ECO:0000313|RefSeq:XP_008302739.1,
GN ECO:0000313|RefSeq:XP_008302740.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000028420.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000028420.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008302739.1, ECO:0000313|RefSeq:XP_008302740.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008302739.1; XM_008304517.1.
DR RefSeq; XP_008302740.1; XM_008304518.1.
DR AlphaFoldDB; A0A3B5B5I5; -.
DR STRING; 144197.ENSSPAP00000028420; -.
DR Ensembl; ENSSPAT00000028880.1; ENSSPAP00000028420.1; ENSSPAG00000021364.1.
DR GeneID; 103374429; -.
DR CTD; 55749; -.
DR GeneTree; ENSGT00530000063672; -.
DR OrthoDB; 12201at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR045354; BURAN.
DR InterPro; IPR025224; CCAR1/CCAR2.
DR InterPro; IPR025954; DBC1/CARP1_inactive_NUDIX_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR045353; LAIKA.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR025223; S1-like_RNA-bd_dom.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR14304; CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN; 1.
DR PANTHER; PTHR14304:SF14; CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1; 1.
DR Pfam; PF19257; BURAN; 1.
DR Pfam; PF14443; DBC1; 1.
DR Pfam; PF19256; LAIKA; 1.
DR Pfam; PF14444; S1-like; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM01122; DBC1; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000313|RefSeq:XP_008302739.1,
KW ECO:0000313|RefSeq:XP_008302740.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891}.
FT DOMAIN 728..762
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 257..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1229..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..123
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1129..1205
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 257..279
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..391
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..449
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 949..984
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1252 AA; 142921 MW; A48ED27BCCA37007 CRC64;
MAQFGGQKNP PWATQFAATA VSQPGHSGQS LDLNSLHSLG VQQPSLLGAS PSVYSQQSAL
AAASLSNQSA ANYQLSQQTA ALQQQAAAAA AAALQQSQIN TALQQYQQQQ QQQQQQQQQQ
QQQQQPPQQP PQQQLYNVPH QLPQPQQALL SQPPVALPTS LSLSNPQQTA QITVSYPTPR
SSHQQQTQPQ KQRVFTGVVN KLHDTFGFVD EDVFFQLSAV KGKTPQVGDR VLVEAVYNPN
MPFKWNAQRI QTLPQLANQS HQQQPQPLPQ ASPQLGSLYN EPGMQLRYSD MHSTADNRQN
NQPQAPNMMK AAPTMLQSLP PPTTFSVPAQ APPPSLLQAQ LSAASLAPLL QNPPQPLLPQ
PPPKDVFPGG LLQPPVRMMP QPQPVRRIEP PPRFPTRNDR GPELILRSKE ERSRDRDRER
RRSRERSPTR KRSRDRSPRR DRSPRRPRRV VPRYTVQFSK FSLDGSSCDM MELRRRYQSL
YIPSDFFDAV FTWVDAFPLT RPFQFSNACN FHILHKEVDP LVKNTAVLDP PDANHTYSAK
VMLLANPSIE ELYHKSCALA EDSQELRDSF QHPARLIKFL VGMRGKDEAM AIGGHWSPSL
DGADPEKDPS VLIKTAIRCC KALTGIDLSL CTQWYRFAEI RYHRPEETHK GRTVPAHVET
VVLFLPDVWH CLPTRSEWEV LSRRLREQLA EKLSAERKEA DGEQEEEEKD DDESKDVSTP
THWTKLDPKS MKVNDLRKEL DCRSLSSKGL KSQLIARLTK QLKVEEQVEE SKEPEKPECK
IAEEEEPTRP EDDREEEERK RQEELERQRR ERRYVLPDEP TILVHPNWAA KNGKFDCSVM
SLSVLLDYRL EDNKEHSFEV SLFAELFNEM LQRDFGYRIY KALAALPTKE EKKEKKAKKE
AEKKEVEKRE IKKEKEEENE EPAAKKTKED DEEKKKYDEK VVKKEESRDE EENEDDSSMT
NNEEYDPMEA EDADDDEDDD KDDEDSNDRD RKDRKDDRKS SKERSSKDKE KKQMVTHNKE
LLMAFVYFDQ SHCGYLLERD LEEILYTLGL HLSRAQIKKL LNKPVVRESC YYRKLTDRGK
DEPLPSFNEA LIENLIGNRG LLPAPKARAQ SEASECGNLI VYNGAMVDIG SMMQKLEKSE
KAREEIEQKL MLQDAKMDED AKVKGQLEQA NKALSRELED VKSTLSQTEQ TLKAAEEQKT
IYHEQMSRSA TSLMSTVKGL LAVLKKDQEV DESGDEVTGD HIQTSQTNGA DE
//
