ID   A0A3B5B5Z2_9TELE        Unreviewed;       699 AA.
AC   A0A3B5B5Z2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000025509.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000025509.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins.
CC       {ECO:0000256|RuleBase:RU004357}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251,
CC       ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
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DR   AlphaFoldDB; A0A3B5B5Z2; -.
DR   Ensembl; ENSSPAT00000025928.1; ENSSPAP00000025509.1; ENSSPAG00000019244.1.
DR   GeneTree; ENSGT00940000164020; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 4.
DR   Gene3D; 2.60.40.60; Cadherins; 5.
DR   Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR   InterPro; IPR039808; Cadherin.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR000233; Cadherin_Y-type_LIR.
DR   InterPro; IPR027397; Catenin-bd_sf.
DR   PANTHER; PTHR24027; CADHERIN-23; 1.
DR   PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR   Pfam; PF01049; CADH_Y-type_LIR; 1.
DR   Pfam; PF00028; Cadherin; 4.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 5.
DR   SUPFAM; SSF49313; Cadherin-like; 5.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043};
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW   ECO:0000256|RuleBase:RU003318};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003318};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          15..100
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          109..203
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          216..305
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          315..411
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          411..532
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   REGION          569..604
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          627..681
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..659
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..681
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  76863 MW;  23DC0D567F8F8108 CRC64;
     MDVNCNLNGL LRHTTVMSSD PDKDADQEAL RYSLHGQGAE SEFIIDEVTG KIYAQRTLDR
     EERAVWRFVV LATDEGGEGL TGFTDVIINV WDINDNAPIF TCAPSCHGEV AENSVIGTSV
     MEMTATDLDD SAVGQNAVLS YRIVEMFTIN PTTGTITVGM GGLDREQVES YLLVVEARDG
     VGMTGTGTAT IQIKDVNDHA PRFTDHSCTA RISENVLELA AEDKDTGENA QLTFSVVAGD
     QEQKFYMVSH KQEQRGTLRL KKRLDYERHN EQRFNLTLKV EDLDFSSLLH CVVEVEDYND
     HAPVFIPHFL SLAPLPEDIT VGTSVARLVA SDSDSGQNRE ITYSLSEESD PEGLFTINQS
     GVLSVARPLD RERIPQHHLV VIATDHGVPP LIGSATVQLP LLDVNDNGPE FEAAYSPVVF
     ENVAGPQVVR LNQTSSLLRA VDQDSPENGP PFHFTVPAEY RHSNDFYLQD NLNGTATLTA
     LRTFDRERQK EFLIPIIMSD SGRPAKTVTS TLTVTIGDQN DHAHVAGEKK IFINMLMNLH
     RLKEGVYHVS AHHDGWEDIR ENVLNYDEEG GGEEDQVQPP RHTHVPPTRL PAQGQARPSQ
     LARRSLSFSS QDLARYLCEI IRDADQHPDT GPFDSLQVFS TEGGGSPAGS LSSFSSAGLD
     GGSGGDGGGE PRREETLGEW GPRFEKLRAL YERAEASDL
//