ID A0A3B5B9A0_9TELE Unreviewed; 449 AA.
AC A0A3B5B9A0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Gastrin/cholecystokinin type B receptor {ECO:0000256|ARBA:ARBA00019090};
DE AltName: Full=Cholecystokinin-2 receptor {ECO:0000256|ARBA:ARBA00031093};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000026679.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000026679.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR AlphaFoldDB; A0A3B5B9A0; -.
DR STRING; 144197.ENSSPAP00000026679; -.
DR Ensembl; ENSSPAT00000027117.1; ENSSPAP00000026679.1; ENSSPAG00000020061.1.
DR GeneTree; ENSGT01100000263563; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015054; F:gastrin receptor activity; IEA:InterPro.
DR CDD; cd15979; 7tmA_CCK-BR; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR009126; Cholcskin_rcpt.
DR InterPro; IPR000314; Gastrin_rcpt.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24238; G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24238:SF74; GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR01822; CCYSTOKININR.
DR PRINTS; PR00527; GASTRINR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 75..390
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 449 AA; 49982 MW; 9ACF9800E26D42FF CRC64;
MDLYAPNETS LNPECVGAQA DALHNGAGNG SLETSSIACG NASTVFIPQR VRQRDEDHTL
RILLYSLIFF LSVFGNLLII VVLTVNKRMR TVTNTFLLSL AVSDLMMAIF CMPFTLIPSI
LKDFIFGAAM CKIVSYLMGI SVSISTFSLV AIAIERYSAI CNPLKSRAWQ TRSHAYRVIA
ATWVLAFVIM IPYPIISHLE SFQRPDNSTA HQCRHKWPVA TAEQTWYILL LLVLFAIPGV
VMIVAYGLIS RELYRGIQFE MGHKKDSTDV KNGLTATVSS GSDDGDGCYV NVVQRPHSME
MSAMATSGRA IKAERPRSNT SEAKLEAKKR VIRMLVVIVV LFFLCWMPLY CANTWRAFDD
VSAKHALSGA PIAFIHLLCY TSACVNPIIY CFMNTRFRKA LFATFSCCAA PCHRRHRRGL
RDNEEDVMAT GASMSKFSYT TVSTMGTYL
//
