ID A0A3B5BB31_9TELE Unreviewed; 674 AA.
AC A0A3B5BB31;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Forkhead box K1 {ECO:0000313|Ensembl:ENSSPAP00000030693.1};
DE SubName: Full=Forkhead box protein K1 {ECO:0000313|RefSeq:XP_008287343.1, ECO:0000313|RefSeq:XP_008287344.1};
GN Name=foxk1 {ECO:0000313|RefSeq:XP_008287343.1,
GN ECO:0000313|RefSeq:XP_008287344.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000030693.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000030693.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008287343.1, ECO:0000313|RefSeq:XP_008287344.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_008287343.1; XM_008289121.1.
DR RefSeq; XP_008287344.1; XM_008289122.1.
DR AlphaFoldDB; A0A3B5BB31; -.
DR STRING; 144197.ENSSPAP00000030693; -.
DR Ensembl; ENSSPAT00000031188.1; ENSSPAP00000030693.1; ENSSPAG00000023026.1.
DR GeneID; 103362689; -.
DR CTD; 221937; -.
DR GeneTree; ENSGT00940000159507; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd20054; FH_FOXK1; 1.
DR CDD; cd22688; FHA_FOXK; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047394; FH_FOXK1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45881; CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR45881:SF4; FORKHEAD BOX PROTEIN K1; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 84..137
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 291..386
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 291..386
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 208..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 72275 MW; 6AFAD0F8D1832069 CRC64;
MADYRDDTGA RALLALQSAP CSPVRVAVTS HAYHQPSLAL LGPPMMEART DAGILPVRLA
SPLSQALARL EGRDFEFVMR QRTVTIGRNS SHGSVDINMG HSSFISRRHL QITYDEANGF
SLRCLGKNGV FVDGVFQRRG APPLPLPREC VFRFPSTVIK IQFMSLLEIE EHREKEQPSP
PPRQLLPHIS PLKISIPTVQ QHEEHIRAFG SPLPSPTGTL SVPNSCPASP RGAGSSGYRY
GRNVTSDLQL AAEYAAKAVS EQRRSIAEQR SGGSEQRGES AGGDSPKDES KPPYSYAQLI
VQAISSAPDK QLTLSGIYAH ITKHYPYYRT ADKGWQNSIR HNLSLNRYFL KVARSQDEPG
KGSFWRVDSA SEAKLVEQAF RKRRQRGVAC FRTPFGPLSS RSAPASPTHQ GLLSPPSSGL
QTPECLSREG SPIPHDHHEQ LASKLASVPE YRYSQSAPGS PVSAQPVIMA APPHPTILPS
GPGKALALVP GGGGQVQPIH VLQTPPQSSV TMVRVVTSAP PNGYSAPTVG GVEGNSDLRD
AQLNRERVIQ TVDSVVQGGE GRNLTPGLHQ LPVRPVTQNG KHTTSAVATA TSLANASGLS
SPLQILAAQA SSSPPVLVSR QPSAETLAGQ AGEPQAKRPK MEDEGGTESA QHQVAPAQQP
VIVAMTSQTH DPRQ
//
