ID   A0A3B5BB93_9TELE        Unreviewed;       333 AA.
AC   A0A3B5BB93;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Neurofilament heavy {ECO:0000313|Ensembl:ENSSPAP00000023037.1};
GN   Name=NEFH {ECO:0000313|Ensembl:ENSSPAP00000023037.1};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000023037.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000023037.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B5BB93; -.
DR   Ensembl; ENSSPAT00000023412.1; ENSSPAP00000023037.1; ENSSPAG00000017217.1.
DR   GeneTree; ENSGT00940000161893; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0005883; C:neurofilament; IEA:InterPro.
DR   GO; GO:0061564; P:axon development; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR033183; NF-H.
DR   PANTHER; PTHR23214:SF1; NEUROFILAMENT HEAVY POLYPEPTIDE; 1.
DR   PANTHER; PTHR23214; NEUROFILAMENT TRIPLET H PROTEIN; 1.
DR   Pfam; PF00038; Filament; 1.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754}.
FT   DOMAIN          31..333
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   REGION          253..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          42..185
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        253..274
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   333 AA;  38603 MW;  36F734F831E120AE CRC64;
     MHTHTHLKQA NKVQGLNCIT AESSWRLPGH EKEILQALND RFAGYIDKVR NLEMHNRNLE
     AEAAALRQSQ AGRASVGEHY ERELGDLRGL LQQLTGEKAR AALEHEHLEE DIQHLRVRLE
     DEARNREELE AGVRAMKKYV EECRLARLEL DKKMRALEEE ATFLKKNHEE EVMELLAQIQ
     GAQVSFDMRD ALKADVTSAL REIRSQLDTH ASKSATHAEE WFKGELDQRG SKEIAEYRRQ
     LQSRTIELET LRGTKESLER QRMESEDRHQ DDLGSLQAGH QCRRAITNLD NELKTTKWEM
     ASQLKDYQEL LNVKMALDIE IAAYRSVRVR KHT
//