ID A0A3B5BCP8_9TELE Unreviewed; 377 AA.
AC A0A3B5BCP8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=General transcription factor IIH subunit {ECO:0000256|PIRNR:PIRNR015919};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000030711.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000030711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR015919}.
CC -!- SIMILARITY: Belongs to the GTF2H2 family.
CC {ECO:0000256|PIRNR:PIRNR015919}.
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DR AlphaFoldDB; A0A3B5BCP8; -.
DR Ensembl; ENSSPAT00000031205.1; ENSSPAP00000030711.1; ENSSPAG00000023036.1.
DR GeneTree; ENSGT00490000043395; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0000439; C:transcription factor TFIIH core complex; IEA:InterPro.
DR GO; GO:0005675; C:transcription factor TFIIH holo complex; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR007198; Ssl1-like.
DR InterPro; IPR004595; TFIIH_C1-like_dom.
DR InterPro; IPR012170; TFIIH_SSL1/p44.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR NCBIfam; TIGR00622; ssl1; 1.
DR PANTHER; PTHR12695; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2; 1.
DR PANTHER; PTHR12695:SF2; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED; 1.
DR Pfam; PF07975; C1_4; 1.
DR Pfam; PF04056; Ssl1; 1.
DR PIRSF; PIRSF015919; TFIIH_SSL1; 1.
DR SMART; SM01047; C1_4; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRNR:PIRNR015919}; Nucleus {ECO:0000256|PIRNR:PIRNR015919};
KW Transcription {ECO:0000256|PIRNR:PIRNR015919};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR015919};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRNR:PIRNR015919}.
FT DOMAIN 345..365
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT ZN_FING 276..293
FT /note="C4-type"
FT /evidence="ECO:0000256|PIRSR:PIRSR015919-1"
SQ SEQUENCE 377 AA; 42202 MW; B1FCC9368F051DB7 CRC64;
MDEEPERAKR WEGGYERTWE VLKEDESGSL KATVEEILYQ SKRKRVIESH GQVRLGMMRH
LFVVIDCSRS MEDQDLKPNR LTSTLKLPVC DIMHIQCKVI CFVSPSGNPK KHIAALKKAV
DTVCVGEPSL YNSLNLAIQT LKHMPGHTSR EILIILSSLT TCDPANIYEM TKVNIMYMLL
TFLICSTDNL SCSLNVRVSI IGLSAEVRVC TVLTRETGGS YHVILDESHF KELLTLHVKP
PPTSSSSECS LIRMGQYRLE NCDFTLVGLS LGGYFCPQCH SNYTELPVEC KVCGLTLVSA
PHLARSFHHL FPLEAFIESP VEELQGNGFC QACQGELKDK SIFTCPSCRS VFCVECDLFI
HDSLHCCPCC IHSQTAS
//
