ID A0A3B5BDK3_9TELE Unreviewed; 2625 AA.
AC A0A3B5BDK3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000023887.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000023887.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR STRING; 144197.ENSSPAP00000023887; -.
DR Ensembl; ENSSPAT00000024269.1; ENSSPAP00000023887.1; ENSSPAG00000017891.1.
DR GeneTree; ENSGT00940000164265; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0005930; C:axoneme; IEA:UniProt.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46961:SF21; DYNEIN HEAVY CHAIN 5, AXONEMAL; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 32..168
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 311..466
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 636..784
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 1263..1336
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1484..1546
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1817
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2625 AA; 294726 MW; 815EE45DB3D4DD3F CRC64;
TRRSSPSTST RETSLTTWCY ITLAQALGMS MGGAPAGPAG TGKTETTKDM GRCLGKYVVV
FNCSDQMDYR GLGRIYKGLA QSGAWGCFDE FNRIELPVLS VAAQQIYIVL QCKKNKKKQF
VFTDGDVVDM DPEFGIFLTM NPGYAGRQEL PENLKIQFRT VAMMVPDRAI IMRVKLASAG
FRDNQVLSRK FYTLYKLCEE QLSKQVHYDF GLRNILSVLR TLGSVKRSNP SEPEKTVVMR
VLRDMNLSKL VDEDEPLFMS LINDLFPGIV LDKAGYPDLE ASIVRQAQQA GLIPHPPWTL
KLVQLYETQR VRHGMMALGP SGAGKSACIL TLMKAMGECG APHREMRMNP KAVTASQMFG
TLDVTTNDWT DGVFSTLWRK TLKAKKGENI WIVLDGPVDA IWIENLNSVL DDNKTLTLAN
GDRIPMAPCC KIVFEPHNID NASPATVSRN GMVFMSSSVL GWSSILQAWL QKLPEQQADS
LKRCFHCCYQ DLLDFVSTAV SPKMQVLECM YIRQTIDLLQ GLLPAVEDKQ GCHGDVGRLF
VFAVMWSLGA LLELDDRAKM EAFLKGYSSS LDLPPTQDEQ TMFEFTVGEQ GQWQHWSDKV
PDYVYPKDHV PDYSSILVPN VDNVRTDFLM RTIMKQGKAV LLIGEQGTAK TVMIKGYTGK
LDPELHLSKT LNFSSATLPG MFQRTIESYI DKRMGATYGP PAGRRMTVFI DDINMPVINE
WGDQITNEIV RQLMEQRGFY SLDRPGEFIT VVDVQLVAAM IHPGGGRNDI PQRLKRQFSV
FNCTLPSNSS IDKIFGTVAQ GYFCPERGFP QAVCELAAAL VASTRRVWQA VKAKMLPSPA
KFHYIFNLRD LSRIWQGILT VKSEVCRSSD LLAALFHHEC SRVIADRFVD SSDRQTFTSI
MEKITVEDHG RALTEHAQWN SCFVDFLRDA LEATGDDPEE TELEAPKVYE PVPSLDVLAE
RLALFQQQYN EAARGGAMDL VFFKDAMKHL MRISRILRTP QGNALLVGVG GSGKQSLTRL
ASFIAGYQTF QITLTRSYSS SNLLEDLKFL YRVAGQQGKG VTFIFTDNDI KDESFLEYMN
NVLASGEVSN LFARDELDDI GQDLVPVMKR HSPRRAPTPE NLHDFFLSRV RSNLHVVLCF
SPVGEKFRTR ALKFPGLVSG CTVDWFQRWP RDALTAVSHH FLSQYQDLRC SEDMRRSVVV
AMGTFQDLVA EKCGEYFERF RRPTFVTPKS FLSFIDSYKV IYGEKIAHVG TLAERMKTGL
CKLMEAEQEV SRLSDQLLLK EQELAVASRR AEGVLQEVTA KAQAAEKVKQ QVQKVKDKAQ
LIVDEIEADR TAAESKLEAA KPALEAAEAA LQTIRPADIS TVRKLQKPPH LIMRIMDAVL
LLFQRKVSDP VTADPERPCP RPSWAEAMKL MQNSSFLHQL LSFSKDSITA EVVELLAPYL
DMDDYNMESA KRICGNVAGL CSWTQAMVDF FSINKEVLPL KANLALQEAR LLVAQAELAK
AQDQLDAKQQ ELDAVQALYD AAMKEKQDLQ DDAQTCRRKM SNATALIDGL GGEKVRWTDS
SAGFQTQIRN LVGDVLLSTG FLSYAGPFNQ EYRRLLLELW KKDMEDKRIP FSPGLNVIGL
LVDGATVSEW NLQGLPGDDL SVQNGIVVTK ASRYPLLIDP QGQAKTWIQN REREQQLQVT
SLNHKYFRSH LEDSLSLGRP LLLEDVGEEL DPVLDNVLDK NYIRSGSTYK VKVGDKEVDV
MQGFRLYITT KLANPAYSPE VSARTAVVDF TVTRRGLEDQ LLGRVILLEK QELEAERVKL
LEEVTSNRRR MQELEDSLLL RLTSTQGSLV EDESLIQVLR VTKSTAQEVS EKLSVAADTE
VKITRAREEY RPVATRGSIL YFLVVEMSLV NVMYQTSLRQ FLGLFDSSMR NSAKSQLTSK
RISSIVDFLT CQVFCYTARG LYEEHKLLFT LLLALKIDLQ ARNISQPELL TFIKGGASLD
LNSVEPKPRR WILDQTWLNL VQLSALPPFS RILIQVRNER SWRTWFDQPA PEEAPLPDGY
EEKLDAFRKL LLIRSWCPDR TTAQAWHYIS ESLGQRYAEG LVLDLDAMLA ESDNRTPMVC
LLSMGSDPTE NIERLAKSKG APCRPISMGQ GQEVHARRLL ANSMTDGGWL LLQNCHLGLD
FLDELLETVT AATPDDVHAG FRVWLTTDVH DRFPITFLQS SIKFTNEPPL GRTGSASLSP
NDIFPPCDPG EVQYGGRVTD DLDKRLLNTF TRVWFGGNTF SDKFCFYRGY SIPAEARTVQ
DVLQHIDALP LVDSPEVFGL HPNADITYQT NLANETLSTI ISIQPKDGGG GAGETREASV
QRLANEMLEK LPPDYVRHEV KGQLQKMGPL QPMNIFLRQE VDRMQRVISS VRSTLSDLKL
AIDGSIIMSQ DLRDALDCVF DARIPRLWLR LSWPSASLGF WFTELLERNQ QLHAWISAGR
PNQFWLTGFF NPQGFLTAMR QETTRSNLSR GWALDTVTLS NDVTKMMRED VSAPPPEDVG
GVYIHGLFLD GAGWDRRGAK LAEAPPKVLF TPLPVVHVYA VNAANMADRK QPAGGGVAAL
SLYSCPVYKK PRRTDLNFVF CLQLRSVQPA DHWTLRGAAL LCDCK
//
