ID A0A3B5BFC7_9TELE Unreviewed; 1983 AA.
AC A0A3B5BFC7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Disks large homolog 5-like {ECO:0000313|Ensembl:ENSSPAP00000024797.1, ECO:0000313|RefSeq:XP_008296925.1};
GN Name=DLG5 {ECO:0000313|Ensembl:ENSSPAP00000024797.1};
GN Synonyms=LOC103369863 {ECO:0000313|RefSeq:XP_008296925.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000024797.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000024797.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008296925.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008296925.1; XM_008298703.1.
DR STRING; 144197.ENSSPAP00000024797; -.
DR Ensembl; ENSSPAT00000025206.1; ENSSPAP00000024797.1; ENSSPAG00000018681.1.
DR GeneID; 103369863; -.
DR GeneTree; ENSGT00940000155303; -.
DR OrthoDB; 2877432at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd00992; PDZ_signaling; 4.
DR CDD; cd11860; SH3_DLG5; 1.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR006907; DLG5_N.
DR InterPro; IPR035537; DLG5_SH3.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46360; DISKS LARGE HOMOLOG 5; 1.
DR PANTHER; PTHR46360:SF1; DISKS LARGE HOMOLOG 5; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF16610; dbPDZ_assoc; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 4.
DR Pfam; PF04822; Takusan; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 4.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 4.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..92
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 691..780
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 775..866
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1406..1485
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1566..1646
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1657..1725
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1803..1969
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 106..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 927..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1256..1405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1490..1557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 183..252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 301..404
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 433..670
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 106..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..964
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1060..1082
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1091..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1141..1165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1256..1283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1294..1324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1341..1386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1983 AA; 222627 MW; 6CA27430EC187AB8 CRC64;
MEPKHKELLE KCYQNLVESV TDADRVVDVL AHCGTLSPAE RYELGHSCSS NSEKVDLLLK
ILLSKDRDHF AEFCAALEAT HPHLHAVLLN GTGPVDHTTG STYSVLSTMP SDSESSSSLS
SLASSPPPAH MEGHQVSEKM ETVLFQLRHV TRERDDLRKR LALSSPGTTF DDCRPNAKAG
HDYERLKLQC MKAMADLQSL QNQHSTTLKR CEEAVKKADF YHTLHSRLAS EHTQLKEELE
AVRQDNIQLV REHNHVKQAC EELRRLHDDD QREVADMRML HQQVMREGSS DVLNKLYDTA
VDKLEAMKSD YEALRKHYND KTANHNADLS RLDQAEEENH RLQKQLDMLL KQRDAAIHYQ
QQYSSSIRRF DNTQQELSKA AAQNKELQRE MDRLQSETTR LKTQQLKAAK DCEKFKEERD
SVISEYRLIM SERDQVIKEV DRLQTGLEVA EAKLKNTSSE RRVANEELEA LRQELASSLV
DRDRAVCEKN ELLEKYCHEV KDKTEAQKEL SQACKDIETV REERDVARKE RTEAIIQRDQ
LLREYYQARQ KQDCATLDME RANKEIDMLR KQYEAISQEL KEALQEAEVA KCRRDWAFQE
RDKIVAERES IRTLCDNLRR ERDRAVSDLA DALRNLDDTR KQKNDAAREL KELKEKLEDQ
LEKEARYRQL MAHSSHDSAI DTDSMEWETE VVELEKHRDM DLKALGFDIA EGVNDPYLPG
DCGIFVTKVD KGSIAEGRLR VNDWLLKIND VDLTNKDRKQ VIKTVLSGEG VINMVVRRRK
SLGGRIVTPV QINLAGHKDS GIGLESGVFV ATLASGSPAA RDCNLTVGDR LLAINGIALE
NKSLSECESL LRNCRSSLSI SLMKFLPQSS SGQSLFETLR DSEKVSRLQT CEVHARNCRN
SKHNCSTQTD MCSCDLGSRE EDTCKDAGDS LDSSSISAHS HHKPFSNSSL HSRSLSTSHS
SSEPHPEFCY RRQDLHHRPF TFTPVHSDCS SPQAAVDQVQ SSPVKASGGT WPKVIAGASL
PECTQLSIYK KPKQRKSIFD VNAFRRPEAA PKLDYMSLSQ LPKHSPQSSL SESAQTPPTP
PARSDSFRFK HRQQNSSASD STITTGTPPA SPAQAASRQD EGEVGNQLYY TDAPPGETKT
SSKKPAEEEG SRRRTEVQEK RRYRPKSAPA LRRNVTPLHI PVPMQVQSFS NDEHSPEPMD
LLRFSPMRTN RYSMQFAPPS YGSVAAHPAA QRGLAPCPAV TAVMRNPVYT AWSHEVQTSN
CPPAPSSGIH PHSHTSPQHQ GRLSLDLSHK RTGDLAETSC SQPPHSTHSL PSSARLSSSG
TLQFRAERIK IPPARYPRST GSDRGSLSHS ECSSPTPPMS PVNLETSSFT SSQSQSSIST
QPRISVSPAP VGDRRKDGPY LEEPRNVTVQ KGAEPLGISI VSGENGGVFV SKVTAGSIAH
QARLEYGDQL LEFNGINLRN ANEQQARLVI GQQCDTVTIL AQYNPHMFQL GNHSRSGSRM
ESISNQPTPR DSGATTPDNH STVDTLSEQD EGTMTPPSKQ TTPATSPHSS FRLPGSLTHR
TSESRLVRLK RIHVELGVQI CGGNLYGIFV ESLDDDSPAK SADGLLAGDL IVEYNGISMK
NKTKEDAYLE LLKPAETITF KVQNRAHSFG EIKESPGDGF FIRALYEKVA EAEQELSFKK
DDILYVEDTL PNGNFGYWMA WQLDENAQKL EKGQIPSKYM MDQEFYRRHS MADMKDDNGT
SKTLSAAARR SFFRRRLKHK RSGSKDGKDL TALDAISTDS LPLTEDGVSL MYQRVQKVEC
SSPRPVLILG PLVEASKDML VKEAPAKFCR CLPEIMKASQ QAIERGVKDC VFIDYKRRSG
HFDVTTVASI KEITEKDCHC LLDIAPHAIE RLHSVHIYPI VVFIRYKNAK QIKEQKDPLY
LRDKLSQKHS KEQFEAAQKV EQEYSRFFTG VVQGGSVSYI CTQIMTIVEQ EQSKVLWIPD
GAP
//
