ID A0A3B5BFU8_9TELE Unreviewed; 935 AA.
AC A0A3B5BFU8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Sorting nexin 14 {ECO:0000313|Ensembl:ENSSPAP00000025132.1};
GN Name=SNX14 {ECO:0000313|Ensembl:ENSSPAP00000025132.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000025132.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000025132.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR AlphaFoldDB; A0A3B5BFU8; -.
DR STRING; 144197.ENSSPAP00000025132; -.
DR Ensembl; ENSSPAT00000025542.1; ENSSPAP00000025132.1; ENSSPAG00000018976.1.
DR GeneTree; ENSGT00950000182856; -.
DR Proteomes; UP000261400; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:InterPro.
DR CDD; cd06877; PX_SNX14; 1.
DR CDD; cd08722; RGS_SNX14; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037436; SNX14_PX.
DR InterPro; IPR037892; SNX14_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF44; SORTING NEXIN-14; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 125..296
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 316..448
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 536..656
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
SQ SEQUENCE 935 AA; 108727 MW; 7D9C9C0A1D64FB86 CRC64;
MGCITAYLQR IRRRMKLERV RELGRQYPVF CFLLLLLLMS TVLLNRYIHI IMVFWSFLAG
VVTFYCSLGP ESLLPNILVS IKPKTKQELF PLGHSCAVCG KIKCKRHRPT LLLENYQPWL
DLKVPSKVDA SLSEILELVL ENFVYPWYRD ITDDEAFVDE LRVTLRFFSA VLVRRTQKVD
VASLITQKLL KVSMKHIEII SKARQKVKNT EFLQQAALEE YGPDLHVALR SRRDELLYLR
KLTEMLFPYI LPPKATDCRS LTLLIREVLA GSVFLPSMDY LADPVSVDSL KAEPEEATEP
TSTLVPFLQN VSFDLELKEI REQQDLLFRF MNFLKQEGAV HVLQFCLAVE EFNDRILCPE
LSDSEKMMLH EEVKKIYETY CLDESVDKIR FDPFIVEEIR NIAEGPYAEV VKLQTMRCLF
EAYEHVLSLL ENVFTPMFCH SDEYFRQLLR GAESPARNSK MSRNTSKRGE SFGISRIGSK
IKGVFKSTTM EGAMLPSYGL VEGEDDMVEE AMMVLEDDSP MEAASTPSTP RNLSAWNITI
PYIDFYDDDV KRERIPVFCI DVERNDRKAV GHETEHWSVY RRYLEFYVLE SKLTEFHGSF
PDAQLPSKRI IGPKNYEFLT SKREEFQEYL QRLLQHPELS NSQLLADFLS PHSMESQFLD
KMLPDVNLGK IIKSVPSKLI KEKGQHLEPF IQSFFNSCES PKPKPSRPEL TILSPTSEND
KKLFNDLFKN NANRSEMTEK RHNQNYFMEM ITVEGVYDYL MYVGRVIFHI PDWLHHLLMG
GRILFKNTLE AYTDYYLQYK LNQVVQEHRL VSLITLLRDT VFCESSPPRS AQDKQRRAKK
TFEEMMSYIP DFLGKCIGEE AKYEGVRLLF DGLQQPVLNK QLTYVLLDIA IQELFPELNK
VNRCKSETWR LNINAATHNL YNLLDPVVMM PGAHE
//
