ID A0A3B5BH52_9TELE Unreviewed; 1066 AA.
AC A0A3B5BH52;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Multimerin-2 {ECO:0000313|Ensembl:ENSSPAP00000030224.1, ECO:0000313|RefSeq:XP_008286550.1};
GN Name=mmrn2 {ECO:0000313|RefSeq:XP_008286550.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000030224.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000030224.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008286550.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008286550.1; XM_008288328.1.
DR AlphaFoldDB; A0A3B5BH52; -.
DR STRING; 144197.ENSSPAP00000030224; -.
DR Ensembl; ENSSPAT00000030717.1; ENSSPAP00000030224.1; ENSSPAG00000022701.1.
DR GeneID; 103362067; -.
DR CTD; 100148368; -.
DR GeneTree; ENSGT01030000234633; -.
DR OrthoDB; 4634169at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR PANTHER; PTHR15427:SF6; MULTIMERIN-2; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF07546; EMI; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1066
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041126068"
FT DOMAIN 66..142
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT REGION 24..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..938
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 328..390
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 144..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..275
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1066 AA; 118292 MW; 39B09C9CAED2B2B7 CRC64;
MTAVGELVLV LGLLVSAHCE VRARDPEVDE EEEELGGRAG GGAFSPHPGG IEDPQMGGTG
SYPSRTGNWC PLVKERVVTT VVACGTEKYT IRSQSPCPSG SPNCQLVMYK LSTRPLYKQK
PKIVTSLLWR CCPGHGGENC EDTVSDPQLD SGSSGLITVS EPERTDVQAP AIKDRLQLQQ
ADPNREQNDH QVAVQVSYDS GYANTQPNAT QPTVGPGHAH KPHHGPHHGT NTYNHHQPHE
PHRPPHQPQE PYRPPHQPQE PYRSPYPPPY QPQDPYSPQE LHRSQEHHQP VVNEMPYPDT
PAALPVPHMM ALVMSQLQPV LEGFNRSLEH LSRQVGDLAR DVAQLKSSQL EAELQAGPAD
GAEERLEVRL DEAFHHIREL RRQLENQRSD MDNRLHSQHA MLHYNLTSFK TDIDMKLKRH
QKMLQVSLQT INTTLSELKF DQDQITEDEL QDRLPPPSPP PPQLPLSSDT SALWEAIERL
DNMVVNNTVK VSGLTEDVEV TSGGVEQLRQ HMKELEKLIN STARKSQVLF METGLEVEDA
KVSVLRRVDE VAGNLTQQDQ RLQDLDVDVD YLYTVFYKHN TSTSCDCKVL TAAVARLEEG
VANVTELANE NRLALDENSE GGAGQWGGAG DWEPAVEALQ HGLQQVKESL TSEQTRTRTL
DLSLTQLSDS VSGLTEADVK LQASMKHLSA SFNSLLKDAI RHSEVLERLL DEEVLEFLDW
PVPDQKAYAV PGLKEQLRQL QDQLKGHDES IRTLQGGGTG VREEVPSADQ PSSSSSSSSS
SSSHPLQDER LPGDMRRSVG GLPARERQLL LQGSDLWNLE KTVEELQQKL LRLEEKPCSC
PDASADGEAR LQAEVTWLKR GLEEHLRVFK NVFSNADVLA ASDNTLELDK LWQLLKNKDE
KKDKRRGGGR EESGRGGGRE ESGRGGRQRS RRDASGVSAP FDQSEAFLLF VARSPLSVSN
SAVVFQPSVN RGRFYSDGGV FTAPVDGLYL FLLTLDLRPG PAHVVLRRGE EGGAPVSLQR
REETEAGLVT GWGLLMLRRG EQVRLELTEG QWEESEDNVF AGLLLH
//
