ID A0A3B5BLH5_9TELE Unreviewed; 743 AA.
AC A0A3B5BLH5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Exostosin glycosyltransferase 1 {ECO:0000313|Ensembl:ENSSPAP00000029217.1};
DE SubName: Full=Exostosin-1 {ECO:0000313|RefSeq:XP_008275210.1};
GN Name=ext1 {ECO:0000313|RefSeq:XP_008275210.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000029217.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000029217.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008275210.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
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DR RefSeq; XP_008275210.1; XM_008276988.1.
DR AlphaFoldDB; A0A3B5BLH5; -.
DR STRING; 144197.ENSSPAP00000029217; -.
DR Ensembl; ENSSPAT00000029686.1; ENSSPAP00000029217.1; ENSSPAG00000021966.1.
DR GeneID; 103353829; -.
DR CTD; 2131; -.
DR GeneTree; ENSGT00940000155321; -.
DR OrthoDB; 1220028at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR InterPro; IPR015338; GT64.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR48261; ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR48261:SF2; EXOSTOSIN-1-LIKE; 1.
DR Pfam; PF03016; Exostosin; 1.
DR Pfam; PF09258; Glyco_transf_64; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 108..393
FT /note="Exostosin GT47"
FT /evidence="ECO:0000259|Pfam:PF03016"
FT DOMAIN 477..726
FT /note="Glycosyl transferase 64"
FT /evidence="ECO:0000259|Pfam:PF09258"
SQ SEQUENCE 743 AA; 85835 MW; 9035728E0046D508 CRC64;
MQAKKRYLLL FSAGACLVLL FCFGGIQVPL SRRGPNRRDD RSLAGFHPGA RWRRLPGYLQ
PFSPWEQDRS DDLNEHISPR QKRDTLSGLY TGKRCRMESC FDFSLCERNG FKVYVYPQQK
GEKLSESYQN ILSSIEGSRF YTPDPAQACL FVLSLDTLDR DQLSPQYVHN LKAKIQSLPL
WNGGKNHIIF NLYSGTWPDY TEDLGFDIGL AMLAKASIST ENFRPNFDVS IPLFSKDHPR
TGGDRGYLKH NTIPPYRKYM LVFKGKRYLT GIGSDTRNAL YHVHNSEDVV LLTTCKHGKD
WQKHKDARCD KDNAEYDKYD YREMLYNSTF CLVPRGRRLG SFRFLEALQA ACVPVMLSNG
WELPFSEIID WNTAAVIGDE RLLLQIPSTV RSIHQDKILS LRQQTQFLWE AYFNSVEKIV
LTTLEIIQDR VLLHTSRSNL MWNSLPGGLF TLPQYSTHLR DFPFYYAKLG IKPHPKFTAI
IHVVTPLVSQ SQPVMKLLVS VAKSQYCAQV MVLWNCDKPL PAKHRWPATS VPVIVIEGES
KVISSRFLPY DTIPTDAVLS LDEDTVLSTT EVDFSFTVWQ SFPDRIVGYP ARSHFWDSNK
ERWGYTSKWT NDYSMVLTGA AIYHKYYHYL YTTYLPASLK TMVDQMSNCE DILMNFLVSS
VSKLPPIKVT QKKQYKETMM GQSSRASRWA DPDHFAQRQT CMNKFANWFG TMPLVHSQMR
LDPVLFKDQV SILRKKYRDI ERL
//
