ID   A0A3B5BLQ2_9TELE        Unreviewed;       819 AA.
AC   A0A3B5BLQ2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Neuroligin-4, X-linked-like {ECO:0000313|Ensembl:ENSSPAP00000029422.1};
OS   Stegastes partitus (bicolor damselfish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Pomacentridae; Stegastes.
OX   NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000029422.1, ECO:0000313|Proteomes:UP000261400};
RN   [1] {ECO:0000313|Ensembl:ENSSPAP00000029422.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964}.
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DR   AlphaFoldDB; A0A3B5BLQ2; -.
DR   Ensembl; ENSSPAT00000029890.1; ENSSPAP00000029422.1; ENSSPAG00000021761.1.
DR   GeneTree; ENSGT00940000156607; -.
DR   Proteomes; UP000261400; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042043; F:neurexin family protein binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007416; P:synapse assembly; IEA:UniProt.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   InterPro; IPR000460; Nlgn.
DR   PANTHER; PTHR43903; NEUROLIGIN; 1.
DR   PANTHER; PTHR43903:SF10; NEUROLIGIN-4, Y-LINKED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   PRINTS; PR01090; NEUROLIGIN.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..44
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           45..819
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017239830"
FT   TRANSMEM        681..704
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          49..611
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          630..674
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          794..819
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        630..657
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  90457 MW;  4A5F615CE63508BA CRC64;
     MRLTITWKQP LICPPPSLSS PLGFPSLLLS LCLTLSLYLA STSAQQTVPV ISTAQGRIRG
     ILTPLPSDLL GPVIQYLGVP YARPPTGDRR FQAPEPPLPW PGIRNVTQFA PVCPQSLDER
     SMLGDMMPSW LTANLDIAAT YLTHQSEDCL YLNIYVPTEE GEWTQKVGRT QTHSCIHIDI
     HEEGGQRPVM VYVHGGSYTE GTGNMMDGSV LASYGNVIVI TLNYRLGVLG FLSTGDQAAK
     GNYGLLDQIQ ALRWVKENIA AFGGDPSRVT VFGSGAGASC VSLLTLSHYS EDLFHRAIIQ
     SGSALASWAV NYQPSKYARQ LGERVGCGID DSTQLVACLQ GRSYRELVEQ NVTPAKYHTA
     FAPVIDGDVI PDDPQILMEQ GEFLNYDVML GVNQGEGVKF VEGIVDSEDG VTAEDFDFAV
     SDFVDSLYGY PEGRDTLRES IRFMYTDWAD RDNAETRRKT LVALFTDHQW VAPAIATADL
     HAQYGSPTYF YSFYHHCQSD ATPPWADSAH GDEVPYVFGV PMVGPTDLFN CNFSKNDVML
     SAVVMTYWTN FAKTGDPNQP VPQDTKFIHT KPNRFEEVAW SKYTPKEQLY LHIGLKPRVR
     DHYRATKISF WLQLVPHLHH VNELLQSVSS FTHSPSPQDD TPSTRHPGSQ GGTPQPPESA
     VGQDGGENGV RVPNEDYSTE LSVTIAVGAS LLFLNILAFA ALLYKKDKRR LEHRRPRPLP
     PPRRDITPAD VAAHLQGEGL MSLQDIYSTL DTVRLTCPPD YTLTLRRSPD DVPLMTSLTP
     GSLPVTPGSH PGYTHHSPYS NTHLPHTHIS THTHSTTRV
//