ID A0A3B5BN58_9TELE Unreviewed; 1389 AA.
AC A0A3B5BN58;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSSPAP00000030627.1, ECO:0000313|RefSeq:XP_008290358.1};
GN Name=ZNF521 {ECO:0000313|Ensembl:ENSSPAP00000030627.1};
GN Synonyms=znf521 {ECO:0000313|RefSeq:XP_008290358.1};
OS Stegastes partitus (bicolor damselfish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Pomacentridae; Stegastes.
OX NCBI_TaxID=144197 {ECO:0000313|Ensembl:ENSSPAP00000030627.1, ECO:0000313|Proteomes:UP000261400};
RN [1] {ECO:0000313|Ensembl:ENSSPAP00000030627.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008290358.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008290358.1; XM_008292136.1.
DR STRING; 144197.ENSSPAP00000030627; -.
DR Ensembl; ENSSPAT00000031122.1; ENSSPAP00000030627.1; ENSSPAG00000022975.1.
DR GeneID; 103364860; -.
DR CTD; 25925; -.
DR GeneTree; ENSGT00940000159287; -.
DR OrthoDB; 3073634at2759; -.
DR Proteomes; UP000261400; Unplaced.
DR Proteomes; UP000694891; Unplaced.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR008598; Di19_Zn-bd.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR PANTHER; PTHR24406:SF30; ZINC FINGER PROTEIN 423; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF13912; zf-C2H2_6; 5.
DR Pfam; PF05605; zf-Di19; 1.
DR SMART; SM00355; ZnF_C2H2; 30.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 9.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 26.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 23.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000694891};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 143..170
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 171..198
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 199..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 272..300
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 310..338
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 340..367
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 508..536
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 544..567
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 663..685
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 693..715
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 723..747
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 751..779
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 781..809
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 812..839
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 838..861
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 929..956
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 973..1000
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1002..1029
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1216..1244
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1303..1330
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1334..1362
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1364..1389
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 902..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1239..1267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..404
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1389 AA; 154827 MW; 180D1BA04501EED4 CRC64;
MSRRKQAKPR SLKEDNVTED QHSPGQTAIP SDPECALERA AEDGETGRLR KRLLSPEEGE
EGEEEDEEPA LHSCDSCRQV FESLSDLTEH KINQCQLTDG ADLEDDPSCS WPASSPSSKD
QTSPGHCEDY DFGEEEGGPG LPYPCQFCDK SFSRLSFLKR HEQSHGDKLP FSCTFCSRLF
KHKRSRDRHV KLHTGDKKYH CGECDSAFSR SDHLKIHMKT HASNKPHKCP VCRRGFLSSS
SLHGHMQVHE RGKDGSSSSL SRADEWKLKE TRKCSRCEEG FDVPEELQRH IAECHPECSP
SEDGGLGATL QCIYCHEPFS DEGTLLTHID QAHSRDRKGH TCAICSEHFM SVEDLYAHMD
IHQLPESSNH SNSPSLLTVG YTSVSSTTPD SNLSVDSSTM VETAPPVPKT RGRRKRAAQN
ATDMGGRSSK QPKVSYSCIY CNKQVFSSLA VLQIHLRTMH LDKPEQAHTC QFCLEVLPSL
LNLNEHLKQI HNAEDHAALL ASLPDALLQC NFCPEVLSDL NALQEHIRCS HGFPSPVAKE
SNAFFCPQCF MGFLTEATLE EHVRQTHCDG GSLRFDSPLA VTPKEPIVEV YSCSYCTNSP
IFNSVLKLNK HIKENHKNIP LALNYINNGK KSLRTLSPSS PISVEQTAML KQGGSASRAT
SEFICNQCGA KYTSLDLFQT HLKTHLDGLQ PQLTCPQCNK EFPNQESLLK HVTIHFTITS
TYYICESCDK QFTSVDDLQK HLLDMHTFVF FRCTLCQEVF DSKVSTQLHL AVKHSNEKKV
YRCTSCNWDF RHETDLQLHV KHSHLENQGR AHRCIFCGES FGTEVELQCH ITTHSKKYNC
RFCSKAFHAI VLLEKHLREK HCVFEGKTQN CGANGSTVSG GDGQPKEDAE LQGLLTNSHG
PGAAVGSVVE SQNSHDGSEE EVDTAEPMYG CDICGASYTM ESLLTNHQLR DHNIRPGESA
MMKRKAEMIK GNHKCNVCSR TFFSEAGLRE HMQTHLGPVK HYMCPICGER FPSLLTLTEH
KVTHSKSLDT GSCRICKMPL QSEEDFLEHC QMHPDLRNSL TGFRCVVCMQ TVTSTLELKI
HGTFHMQKTG TLSANQPMVR SNAITHNQQQ HHPQKLFKCA SCLKDFRSKQ DLVKLDINGL
PYGLCASCVT AAGSKSSSPT VNGGRQQQQH GGATTPATTT AAWIQGESLS PGDGKSKAVS
SSSSSSSTSS SSAAKTRCSS CNVKFESEAE LQNHVQTVHR EQAGDSNSGQ LKTPQVSPMP
RASPSQTEEK KTYQCIKCQM VFYSEWDIQV HVANHMLEEG LNHECKLCSQ SFDSPAKLQC
HLIEHSFEGM GGTFKCPVCF TVFVQANKLQ QHIFSAHGQE DKIYDCSQCP QKFFFQTELQ
NHTLTQHSS
//
