ID A0A3B5JYE5_TAKRU Unreviewed; 730 AA.
AC A0A3B5JYE5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Catenin alpha like 1 {ECO:0000313|Ensembl:ENSTRUP00000050124.2};
GN Name=ctnnal1 {ECO:0000313|Ensembl:ENSTRUP00000050124.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000050124.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000050124.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000050124.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the vinculin/alpha-catenin family.
CC {ECO:0000256|ARBA:ARBA00008376}.
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DR AlphaFoldDB; A0A3B5JYE5; -.
DR STRING; 31033.ENSTRUP00000061115; -.
DR Ensembl; ENSTRUT00000053361.2; ENSTRUP00000050124.2; ENSTRUG00000010980.3.
DR GeneTree; ENSGT01030000234543; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 4.
DR InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR InterPro; IPR001033; Alpha_catenin.
DR InterPro; IPR030045; CTNNAL1.
DR InterPro; IPR006077; Vinculin/catenin.
DR PANTHER; PTHR46342; ALPHA-CATULIN; 1.
DR PANTHER; PTHR46342:SF1; ALPHA-CATULIN; 1.
DR Pfam; PF01044; Vinculin; 1.
DR PRINTS; PR00805; ALPHACATENIN.
DR SUPFAM; SSF47220; alpha-catenin/vinculin-like; 3.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT REGION 691..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 80886 MW; 6B20CD43A46118F8 CRC64;
MASPPCGNSN FDSGLEIKTR SVEQTLIPLV TQITTLINHK DKPKKSERTL AAIHRVGQAV
NVAVGRFVAV GEAIAAENQE LKDEMGQACF EARRAGDAIA QLTDVGAPLP SQQDGGVTVF
SDRTGMVKAA RLLLSSVTKV LVLADRIVIK QIVTSRNKVL VTLDHLERVS TFQEFVQIFS
QFGNEMVEFA HLTGDRQNDL KDEKKKARMA AARAVLEKCT MMLLTASKTC LRHPDCESAR
INKDAVFHRM RCALEQVIEI VTESRSCGEN KILPASIYDG IKDFKSGVEC LRENLYALPL
QSVSGQMEAL VERTEDFTDS PYTSHEQRQA ILGVCQLVRQ DTEQLAHAWV EAQSAHAKEA
TEQVEVAILK TCQSISELRR ELHKVAVGRA SDLLKVHGEQ LPLRALKAAG AEGNLEAVAE
FSRTLTEQKE QLVETCRLLY HVSGSEPLEI TCIHAEETFH VIGPQIISAV QTLALHPSSK
IAKENLEVFC EAWESQLCDM ALLLREINDI FEGRRGDKRP YLSLPRPGYI HICFVSLTIC
GCEQEQTSIA KLGLELRLLS SDVDTEVEKW EEQEHDVVRQ SQSLASMAYN MHLFTRGEGL
LKTTLDLFHQ AEVLSEEGLQ LCSSLRTFST QLVDEEKSSV VTEIEKLAVL CQQLQTGAKT
PAQGKTATFQ KVHALFSLFF LLGSPRDWKE KQEASAADRE EGALNSKNGN GFGVRSLEQH
MAGLNLLESK
//
