ID A0A3B5K328_TAKRU Unreviewed; 1198 AA.
AC A0A3B5K328;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein 646 {ECO:0000313|Ensembl:ENSTRUP00000049912.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000049912.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000049912.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000049912.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B5K328; -.
DR STRING; 31033.ENSTRUP00000049912; -.
DR Ensembl; ENSTRUT00000052447.2; ENSTRUP00000049912.2; ENSTRUG00000025597.2.
DR GeneTree; ENSGT00940000164729; -.
DR InParanoid; A0A3B5K328; -.
DR OMA; RQEQPWE; -.
DR Proteomes; UP000005226; Chromosome 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 15.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR47772:SF5; ZGC:162958 PROTEIN-RELATED; 1.
DR PANTHER; PTHR47772; ZINC FINGER PROTEIN 200; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR Pfam; PF13912; zf-C2H2_6; 2.
DR SMART; SM00355; ZnF_C2H2; 23.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 16.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 20.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 12..40
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 41..63
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 68..95
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 96..123
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 172..194
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 199..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 397..419
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 424..451
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 634..661
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 685..712
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 790..812
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 817..844
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 845..872
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 936..958
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 963..990
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1030..1060
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1072..1094
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1099..1126
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1127..1154
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1156..1182
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 120..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..931
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 860..887
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 125..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 915..931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1198 AA; 134254 MW; A5F57C0020A708C7 CRC64;
MAVRSPGRTT CFPCKQCDMA FPNIPALLDH MEDQHEEERK FKCAECGRGY RHAGSLANHK
KTHEVGSFQC NICGKENSNA LALKSHLRSH TSQKKYSCAH CGKSFRLATQ LNTHKKVHIT
KKVKQQTSKT VDADPSDEPE CDHPHRFSDQ SGSLEMSAEL SETSDDATNR PFKCDLCDKS
YIHQRSLTNH KKTHQVGMFE CTVCFKQFNN MAALYSHQRT HKGKSGADVN ALTGSHTATL
LDNLSRQSQD PQVHFCHLCQ IVFANDEDFQ EHIQMHNSSP LSFGLQDTLS ESQDMSCDNS
ITSPPSDFYA SPLNNGPSVS SVGNFVGFDQ LEENIGRNGH EYPDCSRSDA SPCNIAQGEA
PIMDTSMPNV ALSHTTNPAC VKEVEENSGV DSDERPFKCQ ICGKSYRHSG SLINHKRSHQ
VGIYQCSICR KNYPHLAALK SHLRLHKTQP PSYKMNAEGD GDWLSSEPLT LENQHGCFSS
PGDDDAAAYS VFGTDQENEA EHMKGIVYNE QLNQDVCQDM TLNLPLSQQP VQRHMCADCG
ETFEDIAGIK SHSCPLLQQQ HDTNSSSFDR TVNFLDGDSH CAIGSPGSSV GFHGLNESQD
QSYFEQSFED GLNSYQLNGG EDETDEEEDD GDLYQCSICG NSYTSMRALR SHLRGHTQSH
STPPSSGPSS MSSHEEIKDE PGEMLICSTC GESFASRQDL LSHLLLHQDD NNLQLNFSKV
SGFKEESESI ICGSCGVSCT SYHHLENHSC TTERKNELPQ AEEDTTADEA PQPDASKHVA
ETVESEQRQY KCDQCGRSYR HAGSLLNHKK SHKTGVFRCL VCQKRFYNLL ALKNHQRSHF
DVKRHTCQEC GKAFKIQKQL VNHLKRHKEN QAKIQELNTQ IQALMQMNGS SSEERMQPSP
SVASQTSTSS RPCRRLPQRK KEQIKLEEES QDRRPFACDQ CGRTYRHAGS LVNHRNSHKM
GEYYCSVCNN SYSNRLAMKN HMRTHFAHKR HSCQSCGKGF RGKKQLLTHV CAELRKNGTV
GRRSLRSRTH RCKRCKQAFV SADQLRDHVC SAASGSSEAP TNTSSSKEER PFTCNICNRS
YRHAGSLLNH KNTHKTGHFS CTFCSKPFTN PMALRNHTRI HTQRKKYVCL TCGKAFRLAS
ILHNHQRIHN RAAAHLSCPD CGKRFQGRSG LKRHRCHIGQ DSAGAGTQQP DRGDKCFM
//
