ID A0A3B5KDU5_TAKRU Unreviewed; 279 AA.
AC A0A3B5KDU5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Transcription factor A, mitochondrial {ECO:0000256|ARBA:ARBA00040582};
GN Name=NAGLU {ECO:0000313|Ensembl:ENSTRUP00000053550.1};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000053550.1, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000053550.1, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000053550.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix, mitochondrion nucleoid
CC {ECO:0000256|ARBA:ARBA00004436}.
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DR RefSeq; XP_003978576.1; XM_003978527.2.
DR AlphaFoldDB; A0A3B5KDU5; -.
DR Ensembl; ENSTRUT00000053449.2; ENSTRUP00000053550.1; ENSTRUG00000003631.3.
DR GeneID; 101068883; -.
DR KEGG; tru:101068883; -.
DR CTD; 7019; -.
DR GeneTree; ENSGT00390000005900; -.
DR OrthoDB; 5472820at2759; -.
DR Proteomes; UP000005226; Chromosome 1.
DR GO; GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00084; HMG-box_SF; 1.
DR CDD; cd21987; HMG-box_TFAM_rpt2; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 2.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR48112; HIGH MOBILITY GROUP PROTEIN DSP1; 1.
DR PANTHER; PTHR48112:SF38; TRANSCRIPTION FACTOR A, MITOCHONDRIAL; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF09011; HMG_box_2; 1.
DR SMART; SM00398; HMG; 2.
DR SUPFAM; SSF47095; HMG-box; 2.
DR PROSITE; PS50118; HMG_BOX_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 52..120
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 157..221
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 52..120
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT DNA_BIND 157..221
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 128..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..279
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 279 AA; 32229 MW; 9FB1960166C269D1 CRC64;
MAPFSFMTAT VSCLAKSFTF SCSSYLTRCT CVLPAPYTTA VKNLSSLPSG PPKRPLNGYM
RYVLQQQPMV SKQFPDTKTV DIMRKIAQQW RMLSPEQKQP FEEASLQARE QFKVDLQHYR
EQLTPAQLQQ QSAEKRLKMA QRKASRKKRE LTSLGKPKRP RSPFNIFMSE NFAEARGSST
QGKMKSLLED WKNLLGHQKQ AYKQLAEDDK IRYKNEIKSW EEHMLEIGRE DLIREQTLST
QKNAALKRSP AMKKTKKAKT MVAKTTAKRN LKTPKKMNK
//
