ID A0A3B5KLS2_TAKRU Unreviewed; 465 AA.
AC A0A3B5KLS2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Arf-GAP domain and FG repeat-containing protein 2-like {ECO:0000313|Ensembl:ENSTRUP00000057000.2};
GN Name=LOC101069139 {ECO:0000313|Ensembl:ENSTRUP00000057000.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000057000.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000057000.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000057000.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B5KLS2; -.
DR Ensembl; ENSTRUT00000057633.2; ENSTRUP00000057000.2; ENSTRUG00000023818.2.
DR GeneTree; ENSGT00940000161071; -.
DR Proteomes; UP000005226; Chromosome 8.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08838; ArfGap_AGFG; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46134:SF6; ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1 ISOFORM X1; 1.
DR PANTHER; PTHR46134; DRONGO, ISOFORM F; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 14..135
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 127..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 317..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 49663 MW; ECF83B15D7321A34 CRC64;
MSNRKHRDNQ EICARKVREL AQSGVNKHCF ECGQPGVTYT DVTVGSFVCT SCSGMLRGLN
PPHRVKSISM TTFSQQEVEF LQNHGNEVGR RTWLCAFDPK TDGCPDMKDS QKFKEFLQDK
YEKKKWHFSK SKNRRDAEGP WSPGVQAVPP SHGPMVSQGL SNNLPPNNRP SRPLSQSQLP
SWDRGPVVSP ADMRTDAFTA RPLRSQSFRD PPLKDPSLCG IERQRPGSLS SALGGQSHAF
PALPRPSGRS ISTSGVTGPF RAFPKSLSVD FGGLNHPQGP SLPQSVSQQQ PGGGSQPSGG
GSNAQDRYAA LSQLDSVFSD TAPPGGPPQY STIFGSRLSS NSTPASSPGV DTVSTSQNFA
NFPNPFSSSS QQPVALSPSN PFSNSSGGES GAFVTSPTSI FPPATFPAPS TQKAFHPEST
ANEEANGFAS FPGPDPQPAV PRPMSVNPFT GNVYPSRGAS KNPFI
//
