ID A0A3B5KM55_TAKRU Unreviewed; 1434 AA.
AC A0A3B5KM55;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Jumonji and AT-rich interaction domain containing 2 {ECO:0000313|Ensembl:ENSTRUP00000057140.2};
GN Name=jarid2 {ECO:0000313|Ensembl:ENSTRUP00000057140.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000057140.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000057140.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000057140.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_011607232.1; XM_011608930.1.
DR STRING; 31033.ENSTRUP00000057140; -.
DR Ensembl; ENSTRUT00000053239.2; ENSTRUP00000057140.2; ENSTRUG00000020124.2.
DR GeneID; 105417134; -.
DR KEGG; tru:105417134; -.
DR CTD; 558456; -.
DR GeneTree; ENSGT00940000159220; -.
DR InParanoid; A0A3B5KM55; -.
DR OMA; TGADCIX; -.
DR OrthoDB; 48111at2759; -.
DR Proteomes; UP000005226; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd16870; ARID_JARD2; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR003349; JmjN.
DR InterPro; IPR004198; Znf_C5HC2.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF113; PROTEIN JUMONJI; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF02375; JmjN; 1.
DR Pfam; PF02928; zf-C5HC2; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00545; JmjN; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51183; JMJN; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226}.
FT DOMAIN 714..755
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
FT DOMAIN 778..870
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 1056..1220
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 46..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 957..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1396..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..201
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..283
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 561..582
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 603..661
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1434 AA; 157253 MW; E47ED0DAD2DF8C0A CRC64;
MSKERPKRNI IQKKYDDSDG IPWSEERVMR KVLYLSLKEF RSAQKRQLED GTPNSNGASL
LANGQLNGSG SKNGHKEDGS LRSQGLDGGK YCEDGPAKKR PRLQAQRKFA QSQPNSPSTT
PIKVADTGGL ATVSSSSLSS LSLSSLSSSI QDLSRRKPKT EDFLTFLCLR GSSALPSNIA
YFGSSQEEDD LDEEENEEEE EVRNGGGVHL HSGGSSQAPA TSSCHSTPRK GKPPTRQPLN
GHVFNSHAKA GTRESLRPKA GTHGRDAPAP PLPPPPPPPP PLLRERSERA EAREHARELQ
ALAAGRGSAN GLPSRRAAEE LRKQVSKVNG LTRAGSAQAA GGAKKSRDFR LPSKTVKKYT
ATVSKGHVTY TKAKQRELGK KTKLGSSSKH NSAASAPSSA NNHNQHSQPA ASNGLANSGK
ASAPAHHSNA KTRKQVLLSN GLHNVTVGTR LNGRLNGQRH NALVKEDGQK LYQRQQSQGE
CLGREGLRNS KRRLEVVLNS VGIVEQKAKS SGSEAKRAKV QTAALETRSS SKKMANQERA
AAPATPVSNG HKSDTPSSPK HPSPAASPPS PAPPPQPTPS TPAASAEPVN QRPKRASAGK
LMLIRQAQQQ QSRSHGRSSS SSSPSSGQNQ PQNPSRASTT SDPQQTSESS SNASSPLFPA
NNPGQLKPAA FRSADRDKEW EREKELTRQK EREQEREWER QRSRADGWPA LGEAPVFRPV
PREFLDPLVY LDAVREQAEA AGICRVVPPP DWRPECKLNE EMRFVTQVQR VHMLGRRWGP
NVQRLSCIRK HLKSQGITMD EPPVIGGCEV DLSRFFQLIN DMGGMQQVMD LKKWTKLADL
LRIPKSAQDR LAKLQEAYLQ YILSYDSLSA EERLRLLAEV LQEKKNMETR RGPLEGLSDS
SAPSALVLPR YEPKNGLAGG MVGGATGHHR TNGVYHHLKE LEAQVKAGRR RLFTQEKQGK
EDRQHVEEAQ QEEEDGGVLS DQHKCIYKGK SVSLTNFFRI ARNTMTMCFN KEPGAAEVEQ
EYWRIVEQRD CHVAVHCGKA DTSTHGSGFP TGKSEPFSKH GWNLTVLPNN SGSILRHLGA
VPGVTIPWLN IGMVFSTSCW SRDQNRLPYI DYLHTGADCI WYSVPAEEKA KLDKVVHTLL
QANGTPGLDM LEKNIMISPE VLCREGIKVY RTVQRSGQFV VCYPGAFVSK VCCGYSVSET
VHFATPHWMH LGYQAAKDLK CRRIAKPFSM EKLLYQIATA ESKRDNGFLL TTISTLLKDL
RNIELCQRQE LYKAGLLSSA RYGTHDGNLG PGEGRKKPRG KWLALESSER RCQICQHLCY
LSMVVQETDN VVFCLECALR YVEKHKSCRG LKMMYRYDEE QINSLVNQVC GRAMVKNGSG
GGGVIVSRGG GDPCHGLSPG KASPAKRGPQ KRATVEVSLA RLSSSHIPKA AAVS
//
