ID A0A3B5KPQ4_TAKRU Unreviewed; 329 AA.
AC A0A3B5KPQ4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Phosphatidylinositol glycan anchor biosynthesis class C {ECO:0000313|Ensembl:ENSTRUP00000055350.2};
GN Name=pigc {ECO:0000313|Ensembl:ENSTRUP00000055350.2};
OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX NCBI_TaxID=31033 {ECO:0000313|Ensembl:ENSTRUP00000055350.2, ECO:0000313|Proteomes:UP000005226};
RN [1] {ECO:0000313|Ensembl:ENSTRUP00000055350.2, ECO:0000313|Proteomes:UP000005226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551351;
RA Kai W., Kikuchi K., Tohari S., Chew A.K., Tay A., Fujiwara A., Hosoya S.,
RA Suetake H., Naruse K., Brenner S., Suzuki Y., Venkatesh B.;
RT "Integration of the genetic map and genome assembly of fugu facilitates
RT insights into distinct features of genome evolution in teleosts and
RT mammals.";
RL Genome Biol. Evol. 3:424-442(2011).
RN [2] {ECO:0000313|Ensembl:ENSTRUP00000055350.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the PIGC family.
CC {ECO:0000256|ARBA:ARBA00008321}.
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DR AlphaFoldDB; A0A3B5KPQ4; -.
DR STRING; 31033.ENSTRUP00000055350; -.
DR Ensembl; ENSTRUT00000048853.2; ENSTRUP00000055350.2; ENSTRUG00000023995.2.
DR GeneTree; ENSGT00390000005496; -.
DR InParanoid; A0A3B5KPQ4; -.
DR OMA; STSYHAF; -.
DR OrthoDB; 205848at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000005226; Chromosome 20.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR009450; Plno_GlcNAc_GPI2.
DR PANTHER; PTHR12982; PHOSPHATIDYLINOSITOL GLYCAN, CLASS C; 1.
DR PANTHER; PTHR12982:SF0; PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C; 1.
DR Pfam; PF06432; GPI2; 1.
DR PIRSF; PIRSF016104; GPI2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005226};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 230..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 329 AA; 36461 MW; CD78B0D9174D395D CRC64;
MWRVLGSSPS ADKTWKVFWC RGRGQNISRV MPREMGPDGA PGQVVPWRKV LWEHQPFPDN
YVDRRFLEEL RRNEGIRQYR YWAVVKEAGF VGQQLSSVAI FITLWLYMEQ GLLSPERLLL
TCLLSTLLGY GLHQTLTPLT KSGCELRTRL ADLQSATIFL SFTFGFSPVL KTLTESVSTD
TVYAMSAVML LAHLVSFPYA HPSPPGSLSL NAALFASVCL ASRLPGALHT FAMLSCALLV
FALWPCLLQR LREYAPNQFT GLCVAVCVGG VVGLASQSPG GAVLLALALG TVTLFCPLLL
VRLQRHKDNI HGPWDEAEIH EELGHILHS
//
