ID A0A3B5PUG3_XIPMA Unreviewed; 516 AA.
AC A0A3B5PUG3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Lysosome membrane protein 2 {ECO:0000313|Ensembl:ENSXMAP00000022540.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000022540.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000022540.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000022540.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CD36 family.
CC {ECO:0000256|ARBA:ARBA00010532}.
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DR RefSeq; XP_005798696.1; XM_005798639.2.
DR AlphaFoldDB; A0A3B5PUG3; -.
DR STRING; 8083.ENSXMAP00000022540; -.
DR Ensembl; ENSXMAT00000026488.1; ENSXMAP00000022540.1; ENSXMAG00000024885.1.
DR GeneID; 102228028; -.
DR KEGG; xma:102228028; -.
DR GeneTree; ENSGT00940000153372; -.
DR InParanoid; A0A3B5PUG3; -.
DR OMA; VPNVPML; -.
DR OrthoDB; 315994at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005764; C:lysosome; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR InterPro; IPR002159; CD36_fam.
DR InterPro; IPR005429; LimpII.
DR PANTHER; PTHR11923:SF94; LYSOSOME MEMBRANE PROTEIN 2; 1.
DR PANTHER; PTHR11923; SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1; 1.
DR Pfam; PF01130; CD36; 1.
DR PRINTS; PR01609; CD36FAMILY.
DR PRINTS; PR01611; LIMPII.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 492..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 58064 MW; 01D6B1959D196864 CRC64;
MTRRSCAIYT VGVICALLLV SGIALMVAQV FRNLMHKLLK KEIVLVEGSR VFESWKSPPP
PVFMEFFFFN VTNVEEVLSG KKPEVNQIGP YTYREYRYKD NVTMLDNNTK VSAYNAKSFV
FLRDKSVGDP DVDNITTVNI PIWAAMNKAP GYKSFFLNIM IKGTKSRLFT TRSVQELLWG
YEDALLDRIA SSGTDVERVF GLMYKKNESS DGEFVFHTGT QNYLDYARIE TYKGERMLKY
WSTNESNSIL GSDGSAFHPL LNKSERLYVF SPDLCRTIYM EFEKDVEVKG IPAYRFTPPR
SVLASKEENP ANKGFCVTPK ECLGTGVLKV SPCRKGAPVV ASFPHFYLGE DKYIEAIGGM
APQSHHHQTF LDLNPTTGVI VRASKRAQVN ILINRMSGYP DTKLLKETVF PVMFLNESVV
IDDASAAKVN KLLMIVKVGS NFPLIIVGLS GIMLIVFIIL LIRAHQQKKR VKRIVFTKAA
YATATEEDIS YSPANTKEKD DGQNGNYIGM TTKTEQ
//
