ID A0A3B5PVG9_XIPMA Unreviewed; 658 AA.
AC A0A3B5PVG9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Forkhead box M1 {ECO:0000313|Ensembl:ENSXMAP00000021989.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000021989.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000021989.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000021989.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_014324588.1; XM_014469102.1.
DR AlphaFoldDB; A0A3B5PVG9; -.
DR STRING; 8083.ENSXMAP00000021989; -.
DR Ensembl; ENSXMAT00000027825.1; ENSXMAP00000021989.1; ENSXMAG00000029688.1.
DR GeneID; 102237348; -.
DR KEGG; xma:102237348; -.
DR CTD; 2305; -.
DR GeneTree; ENSGT00940000158804; -.
DR InParanoid; A0A3B5PVG9; -.
DR OMA; APKQEHR; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:InterPro.
DR CDD; cd20029; FH_FOXM; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047516; FH_FOXM1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR042839; FOXM1.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46878; FORKHEAD BOX PROTEIN M1; 1.
DR PANTHER; PTHR46878:SF1; FORKHEAD BOX PROTEIN M1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 215..292
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 215..292
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 19..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 72397 MW; AA042372442DE247 CRC64;
MRRSPRRPLI LKRRKLPFLQ NEPTQADKQT QHCAAGTGEP TKPAASQCLP HGIPIMNHPS
MSDTQVVVIP KEADLQSIIG VLTAKGKESG VQGPNKFILL SESGSRGNGS FCQATVKEES
SPAESTATQP VKSDTIHNMQ DAKPLTGNQS SASCSPLDDS LTNIQWLGKM NTSALEPHLA
NQTIDKEKKL QAPQILQTHN TNSNPEGSHQ PTLQRPPYSY TAMIQFAINS RKNRGMTLKE
IYTWIEDHFP YYREVAKPGW KNSIRHNLSL HDMFIRERSP DGKTSFWTIR PDINRCLTLD
QVYRPCCDPG TVSSPVPLLP CPHQHEKKNI SAVRKVPAST ERRIKPLLPR TDSYLVPIQL
PIASSAYLPS LSGSYCPSGS KHKQNASRGT KRVRIAPKVT EGDSPAVALA PHVDLKVEPV
NVPTKRETRK PPPKRQSSSS RRKQSLVNSL QDEPILLCPD NSFFDSGVVS DASTSQDVRE
ADSTEQQQHF QGSPERELYF KTPIKSHSHL SSSTPSKPPP NVTLEPWKVT PVGKDSQSVL
DFSPIRTPGG PVVTPRQEYT TFSFSSTPFK ELPLFSSPRE LLTPAPCRAP STDSPTEAQL
ADAPAASPSN RSITEGLILD TMNDSLSKIL VDISFSALDD EDLGIANISL SEFLGQFM
//
