ID A0A3B5PXQ1_XIPMA Unreviewed; 715 AA.
AC A0A3B5PXQ1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=GATA zinc finger domain containing 2B {ECO:0000313|Ensembl:ENSXMAP00000022456.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000022456.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000022456.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000022456.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B5PXQ1; -.
DR STRING; 8083.ENSXMAP00000022456; -.
DR Ensembl; ENSXMAT00000037617.1; ENSXMAP00000022456.1; ENSXMAG00000010412.2.
DR GeneTree; ENSGT00390000004097; -.
DR InParanoid; A0A3B5PXQ1; -.
DR OMA; RRCEADH; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 6.10.250.1650; -; 1.
DR InterPro; IPR040386; P66.
DR InterPro; IPR032346; P66_CC.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR13455:SF4; TRANSCRIPTIONAL REPRESSOR P66-BETA; 1.
DR PANTHER; PTHR13455; TRANSCRIPTIONAL REPRESSOR P66-RELATED; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF16563; P66_CC; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00094};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT DOMAIN 509..539
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 44..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 77605 MW; 3F9C9B4C0C713D21 CRC64;
MSNCLTNERS YCLQRRDESL SRPNQRVSAA CRCRGLVVRI RCNASGGPDR EPGDGTQRGE
TTHRMERMSD DTLRLNLLKR GLESSSEREE ALSKRLKMEG HEAMERLKML ALLKRKDLAD
LAALEVPGTL GDGKGPSASS IHHQNLMGAA YEEKLNGSLR LGSHSVHAGQ SKNGKENIMD
EPVDMSAGRR CEVDRDRQTP SPDVIILSDN EASSPRTTPR PEERMHQANL EIFKGKTGEE
RQQMIKALRE ELRLEEARLV LLKKLRQSQM QKENVVQKVP AVQSSASSVQ PPPIHSSSGI
GKLPVRPGLH NTEPQNLRTA QGHTVIRSAN TSLPPMLMSQ RVIAPSPSQL QGQRVSSKPG
MPRSSSSSMT SAVNYQQASQ QVAASQRSSS SAMYMNLAHM QAAAAVGASG VTGGLAGASA
VSPSTMSGSA SGAVSSMADQ ASSQAAAKLA LRKQLEKTLL EIPPPKPPAP LLHFLPSAAN
SEFIYMVGLE EVVQSVLDSQ GKFRGSLARM EPFFCAQCRT DFTPHWKQEK SGRILCEQCM
TSNQKKALKA EHTNRLKNAF VKALQQEQEI EQRLQQQAAL SPSSAATGSN VSKTDTMIRQ
HALRQAQQPQ ASLQRGLSNS ARGVLSNFAQ ASQLSVASSL MGMSSAKHCG SGGSSNRLQH
DSRRQIYNIP GLNIAYLNPA AVGAHKTSSL ADRQREYLLD MIPPRSISQS ITGQK
//
