ID A0A3B5PYB1_XIPMA Unreviewed; 1690 AA.
AC A0A3B5PYB1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Eukaryotic translation initiation factor 4 gamma 1-like {ECO:0000313|Ensembl:ENSXMAP00000023875.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000023875.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000023875.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000023875.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR Ensembl; ENSXMAT00000021288.1; ENSXMAP00000023875.1; ENSXMAG00000016101.2.
DR GeneTree; ENSGT00940000154648; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF10; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 1329..1451
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1524..1690
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1116..1329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 904..931
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 783..797
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1151..1182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1183..1242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1690 AA; 187033 MW; 00CC71E40DAB1418 CRC64;
MNKPPQPITG PTSVPNPSPS PVLNQAAYGP GQPPSLVFAT PPQMNSAQQP RQSYYPSRAT
MAASGPRVQT TSGPRPVAPA HVYPTSSQMM MIPQQQISFG GSPQSYFIPP GQYRTPYMPP
TQQYPVTSGT GFYPGTSPAE YSAYEPSLAA RERRGGGGRG GGRENGRLSL HGAPLTSQRY
PAGAYYPAQP QYSASVQPAQ VMINPQQQAP PPQQAPTQPQ APPKRERKQI TIRDPNQGGR
DITKEIMSGG RSTTTATPPL ASVAEVSVAQ TNGEVVQTVA VVARRDEPVE PSASPESPPP
AAPANTDLVV EAKQEINRPF TPPVELATQS VATTASAERL SPSLKERQSP PSLPSAAAGI
SSVAEAVTMV SSKAGDTVDA PVRPSASPVA QETPLTTEEP QAAPSVEKEV KPEGVQLEKE
EPTASAKSEP PVEVADTPVE TVKEDAFAKP SSNVSQPLAV PEPAASQAED ADQSSEPEPV
EVHPAESPLS NGLPQETEEL SEDVPVSDTT PQDKPDPSQS QESATPAQKE EDEEEETREE
ERPQKKTEDA PLASASCPEE TTMQAATSVP KKKKSMKELN KKAIGGLLDA FEEEPDATPV
PEPSAVQVSP PAPAKPPTET VDETSEEKED KQNAEPDKLE STLDPTEQKY QYKEDLGEPI
NPEAKKRYDR EFLLGFQFSS ASMHKPEGLP VISDVVLDEV NKTPLRPVDP SRLMSAGSDF
TPTFLGGLGG KSAGRPQPSG SHRSQQSLRK EPKKIIIFNS RSLTDNVQLN KAANAWKPST
IKPEDNNPEE ADAEQGKTHE VFKRLRSILN KLTPQKFQEL MKQVMELKID TEERLKGTID
LIFEKAISEP NFSVAYANMC RCLIGLKVPA PDKPGNFVNF RKLLLNRCQK EFEKDQDDDE
IFEKKQKEME ASKNDEERER LRVELEESRD KARRRSLGNI KFIGELFKLK MLTEAIMHDC
VVKLLKNHDE ESLECLCRLL STIGKDLDFE KAKPRMDQYF NQMDKIIKER KTSSRIRFML
QDVLDLRKNN WVPRRGDQGP KTIDQIHKEA ELEEHREQIK VQQQLLSKKD SRGPHTPARG
RVAQSQDEGW NTVPISKNRP IDITRLSKIT KPGALDFNNQ RLAPDGKGMW GSWGKGSSGG
SGAKPASGDQ DSGRPATSTL NRFSALQQSG AMSSSTDTDR RVPQRSSGSR ERGGDRDRND
HDRDRYDRFA RSERQDGNQF SKRSFSRESQ ERGGRGGDSR TTAESVRRVA SMTDNRDRGS
RDRGSRDRGS RDQGGRDRGS RDQGSRDRGS HDRGSRSQSG RDTGPSKDLP VKRESVPASL
PKPAMTEEEV RKKTNAIIEE YLHINDIKEA LQCVAELNSA SLLYVFVSCG LESTLERSTL
ARERMGLLLH RLVEAGTLPV QQYYQGLLEI LEVAEDMAID IPHIWLYLAE LITPMLHDRG
IPMGQLFREI SKPLVPLEKA GLLLAQIIKL LCKGMTHEKV GSLWREAGLN WNEFLSKDED
VNKFVTDQKV EFTTGEETES EEAGRKQILS GDEISKELDR LLQEKANNQR IRDWIEANLD
EQQCASSQFL RSLMTSVCQS AIICDNPYKV DEEQIKERAS LLQRYLCDEE KALQALYALQ
ALMVHMEQPA SLLLMFFNSL YDEDVIDEEV FYKWESCKDP AEQTGKGVAL KSVTGFFTFL
RNAEEESDKD
//
