ID A0A3B5PZG5_XIPMA Unreviewed; 1445 AA.
AC A0A3B5PZG5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Gem nuclear organelle associated protein 5 {ECO:0000313|Ensembl:ENSXMAP00000023967.1};
GN Name=GEMIN5 {ECO:0000313|Ensembl:ENSXMAP00000023967.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000023967.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000023967.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000023967.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 8083.ENSXMAP00000023967; -.
DR Ensembl; ENSXMAT00000021870.1; ENSXMAP00000023967.1; ENSXMAG00000015538.2.
DR GeneTree; ENSGT00620000088064; -.
DR InParanoid; A0A3B5PZG5; -.
DR OMA; CLACCPH; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0070657; P:neuromast regeneration; IEA:Ensembl.
DR GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46362; GEM-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR46362:SF1; GEM-ASSOCIATED PROTEIN 5; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 50..94
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 224..247
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 522..570
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 617..659
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 660..702
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 697..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1312..1349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..795
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1325..1340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1445 AA; 159594 MW; D2B8BEDEA352B7D5 CRC64;
MRERSLPASP NWYSSRCSDV SSSGLLGVGA KSVIYLIEVS AASCRVIGEL VGHRDLVSGF
SFCQHPEQSH ICVSSSTDGS VRFWDSNNKT LIRKNAPHQS PISAVHWSPA DKNLVVSGDE
KGVVVCHWFH TGDTASFFPE PRTIFCLTCS PHSWKSVAVG YKDGMIVLID ISKKGEVMQR
LRGHDNEIHS LAWSPLIGED TLYTRAEDHD ATNGVSAGEE SGCFLASGSK DQTVRIWSTA
KGKGVMTLKL PFLKRRGSAV DPGVKERIWL NVHWPKGRAT QLVSSCFSGE LAMWDLAKNG
KQKWSLFGTS SEGQNHSRIV FNMSSVQLQD GREILISTSM DREIKCWDLD SLSCCWTLPT
LGGHIYTLTF SPVGVGCLAL GVGDNLIRVW NTLSTQNQYD VRSFWQGIKS KVTALAWHPK
KEGSLAFGTD DGKVGIYDVF SNKPPQISSS YHKKTVYTLS WGPPVPPLSF GAEGKQSDSL
YSCAGEGVIL QHDPARLNGE ASDIDKLIRD TNNIQHKLSP HTDLSWKPDG KVVAIGNEDG
SIDVYQAPSL LLLCSIQQHH KIINTLRWHH DHGTAPELHC LLASGSSNAV VYVHDLRSVI
ENPPESPAVL TEPYRRLCGH TAKITSMAWS PHHSGRLVTA SYDGTAQVWD VLEEAAVSNY
RGHTGYLLCV DWSPADPDVI WTGGKDFTVQ EWKVSQQEFT KPPKGKKMAL MQEKKQKKKN
KTASGSVGPA EPRINGEPAT EGKQAEQGLS EEDEEEEVRS SNSLESPAAV NEVPRKSTPA
AKPKDKPDLM KKKKPRSMLP LSTSMDHRPK EELLQDCLTL ASVKHSSAPP AGCVPGRGDY
IHLGLFHDRE ALYCMFEAEE KSHMEAGHYD SVVYLRLWSG DLQGALQLAT ERGELNDHLL
SIAPMAGFEV WSRTVEAFVK QLCLQEQFLK AASHLLSINK LYEAVDLLRS NKLYREAIAL
VKARLPADQP LLKDLYTCWA AVLEKDGHLS AAAKCYLGAG CSFDAAKVIA RKNDAPSLRT
AADLARISGE DVLGQTLALR CSKDLAAAQD WVGAQEVLSS QSPLLAHRLH LCVAELLAAA
LADSGVLAPA SCVSTHRWAT LNGSNTLQDR ARDIWEEEFN VFLNSAGDRS ISALLEELKS
VETPARSASI PLRQVLLYSS VHLTRSLLSW LLSDDGRLMT ELWQAAAWIG DAGHFEVSAA
FCRLLFPEGD VRIFSRKHSK TLHLSEAEAG SLQALVCYHS LYECWWRDSV VQNRPGFCSN
DEPNEAGAAE LKERCSQGLD FEPSVLLSEP HAACQATQRS VRETQERLST MVLQHSRVRD
GRTESGNQQE GSPFQTATSD IEQRSEEEEE TFLSLSSKMS KLQQTLENIP NTIKVIKVGW
RVWIPTIPRD GQLLWMFLSC RCFLVQMWWN VALFSCISTS RLPSQTSFDN RPKICSENTE
PVCLS
//
