ID A0A3B5PZL7_XIPMA Unreviewed; 2474 AA.
AC A0A3B5PZL7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Matrix-remodelling associated 5a {ECO:0000313|Ensembl:ENSXMAP00000024325.1};
GN Name=MXRA5 {ECO:0000313|Ensembl:ENSXMAP00000024325.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000024325.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000024325.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000024325.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_014330579.1; XM_014475093.1.
DR STRING; 8083.ENSXMAP00000024325; -.
DR Ensembl; ENSXMAT00000033802.1; ENSXMAP00000024325.1; ENSXMAG00000003206.2.
DR GeneTree; ENSGT00940000159942; -.
DR InParanoid; A0A3B5PZL7; -.
DR OMA; QPETTKH; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 12.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF4; MATRIX-REMODELING-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 8.
DR Pfam; PF13927; Ig_3; 4.
DR Pfam; PF13855; LRR_8; 1.
DR PRINTS; PR01832; VEGFRECEPTOR.
DR SMART; SM00409; IG; 12.
DR SMART; SM00408; IGc2; 12.
DR SMART; SM00406; IGv; 6.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 12.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 12.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..2474
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017453209"
FT DOMAIN 469..556
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 568..658
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1490..1581
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1587..1683
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1686..1779
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1789..1880
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1885..1987
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1993..2078
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2086..2181
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2189..2279
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2284..2373
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2379..2472
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 674..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 823..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1135..1191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1296..1371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1433..1455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..1036
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1037..1070
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1138..1191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1329..1346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1349..1370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2474 AA; 274100 MW; B853E9ABA55298F9 CRC64;
MKMEHSTLWV LQTLLVLLSP VVSTPCPRPC SCPQPAELHC TFRSLLTVPA AVPKHVKRIN
LGFNSIYKIS DTSLSGLGKL ELLMVHGNNI HSLPDGAFRD LASLQMLKMS YNKLKEINRH
TLQGLWSVTR LHLDHNQIEL IHPDAFQGLT SLRFLQLEGN QLQQLHPATF TTFTLMGQFY
ISTLRHLYLS DNALTSLPFQ LVETIPQLEN LYLHGNPWTC DCSMSWLHDW EKTSPGVLKC
KKDRALSGGQ LCPMCSSPTQ VKEKELQAAH PLVCNSPVIS FLHRITSLEY SESETLTSED
FNEPIGNISL GLSDEHGNEL DLECSAHKLK EPAKVSWEQV NQLQLVANVS FSVDLQCSVD
REKYEQLWRL IAYYSNVPAH LKQLVIPSQE PYPPHVYNQD SVQDAHYYTG LKAKVSAQPA
WLMQPSIELQ LNRPQSSTSM VKLILRTNFS ETVDIKLQQT LRRNWVMIES TNRTQNAMSV
ILGSSNEMAC NVHSSDLPVI QWMLPDSSKL NRPFRSPENR VSVSRDGRLK IKAVTHRDTG
AYYCIAKVQG DFAVLSFYLT VQESSSPPTG EDTSIASIEE FAGNSISLDC PASSSPDAEI
NWILPNNKII YFRANYSKAL VTFNGTLQIL KTQISDSGYY KCVAINQHGV DTLVKKVSIV
RRNGLIRPMR KFTTRPQSAS GVNTQINVPT ENPEEASGDS DGSTIRHRIN SVRRKLPVSL
VPGRRGIHPS RSTWQRQPVF RKPTGSHNGN LKAENRRRIN LSKSKIDPEK WADILAKIRD
RNTVTSPPVS FPTKMKATEL LTQSWETSDE PSDGVTVHER VSQHYSIRQS PEKPTEYSTH
GQDSHVTPES ITAQDATPIS RFVTIEPHPT EIAYTTQHTT YDRELNLITS SNSGFFLPQT
TSVPPHAITV RQPSAHTATS STFSFSENLS TSITADKIQT ADPSEGLQSS ESRNKPNDVT
NSINHREAFF MESQITPSVN PNHSAASQEG SGNYLSETST LSQFQSHPKD TTLNDLHSEV
VDTTGSPTTT FNLPGKRRVH STRRPKSRLR KVNSQRRNGG RRRRPDRKKQ KLKTLGSFIT
TAPVNTPLPT AKTSASKLLN TERSEIAVCL YTSVPFTESQ VASSDRLSHK ESTVFSQNHE
VIKEPSSLPT SSLGTKDSQN KSWQSTAAAP SFPSISPGLT HGNTTPHSTA EISDSAYPTA
ISEILPSIPQ QRFADSPPPP AEHLENWHEI SFTTELAPLL HSESPSWGLQ SMTKLTTDNK
NQQFVHQETF SEEVEQIHWE KTGMDSSLQP SYFTQTASPI QGNKTDSGET SKGSLSTPRM
LFEVTTERLA PLEDLKSEEN EKKPPNAGAD STHMSSVQTT HASATSTLPY HIKPSREIPH
LSKPRLSPLV PLLISLSTSI TQNATVTVST SQDQQIKPIS TTSVLRRSFN FHPTTFPPNH
KPTNTIPTSQ ASTSIPVPTG IPSQKTLSPV TLDVSTQHLN EHGSVQRRKP RIKTTHSQTI
TVKVEKDAKL PCETGGQPMF FLSWTKVSNG ASIARNMKVQ RFEVLHNGTL IIRNSQLTDE
GQYVCTVQNQ YGTDKMMANL IVMSHHPRVL QPRERDIHVY EGSKVELECK VEGDPVPRVK
WVLPNSIQLM TTSPSVPSQW QVAVDDSGTL HINRASLTDS GIYRCTGSSA AGADTVSVHL
HVSAMPSLIQ QRLDENMTFP EGSAAYIDCT ATRASQPTMH WITPDGTQLT PSQLITRDNL
TVFPNGTLHI QRLDLKNSGR YVCKASNGVA SSSRTVMLSI RRKLLSAKAT ITSSSPHRTD
VIYGSKLLLN CVATGEPEPR IIWRTPSKKL VDNQYSFESR IKVFLNGSIS IHSVTDKDGG
DYLCVARNKM GDDYVQLWVN VLTKPATIEQ KLQKSSQEVV QGQDLKVDCV ASGLPSPEIS
WALPDGTMVN PIKQKAGVHV GRSRRYVVFD NGTLYFNDVG QPEEGDYTCY AQNQLGRDEM
KVRVKVKGGT SSPQIQDKDH KTVRVLYGET VTLQCNAKGD PVPVVTWMSP KNRPISNAID
RHKVLKDGTL LVQNVQQFDE GNYTCMARNS VGQDNKVTRV EVLATPLVIN GLRGTSNTIK
VTAVQGERKL LDCVTEGTPS PRIMWILPGN LILPAPYYSN HMTVHQNGTL EIQSAKKTDS
GQMVCVARNE RGEVRMLVNL DVKEMVGHPQ IDAPQRERFS LKVGNTVTLN CSIDGLELTD
IMWTLPSGTP LQAGARISKF FHRLDGSLII NNPSVADVGM YRCVGHNSAG IFESTVTLSP
GRKPQILNRY ISPVSILDGE TLFLHCQTTG EPFKLTWTLP SGVVLNRLQK AGRYSILRNG
TIVIRQASVY DRGPYVCRAA NEYGSSLLSV SVNIIANQPR ITSGPPSVTY AKNGVAVQLN
CVATGLPKVE VAWETPDKTR LVVSAQPRLF GNKYLHPQGS LIIQNPTQRD SGVYRCTARN
TAGVDSKTTF LNVF
//
