ID A0A3B5Q3J4_XIPMA Unreviewed; 842 AA.
AC A0A3B5Q3J4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Zinc finger and BTB domain containing 46 {ECO:0000313|Ensembl:ENSXMAP00000026413.1};
GN Name=ZBTB46 {ECO:0000313|Ensembl:ENSXMAP00000026413.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000026413.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000026413.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000026413.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B5Q3J4; -.
DR STRING; 8083.ENSXMAP00000026413; -.
DR Ensembl; ENSXMAT00000021278.1; ENSXMAP00000026413.1; ENSXMAG00000023594.1.
DR GeneTree; ENSGT00940000158060; -.
DR InParanoid; A0A3B5Q3J4; -.
DR OMA; FTGDGPY; -.
DR OrthoDB; 5343486at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR46105; AGAP004733-PA; 1.
DR PANTHER; PTHR46105:SF20; ZINC FINGER AND BTB DOMAIN CONTAINING 46; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF13465; zf-H2C2_2; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 31..102
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 648..675
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 676..703
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 208..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..352
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..542
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 89912 MW; EA30E8148D53294C CRC64;
MNNRKEDMEI SSHYRQLLRE LNEQRQHGIL CDACVIVDGK IFKAHKNVLL GSSRYFKTLY
CQVKKGAEPP HQTTVTHLDI VTATGFKAIL DFMYSAHLAL TSKNVIEVMS AASYLQMTDI
VQACHSFIKA ALDISIRSEM ADELADFEMG AVAAGLGGGG GVSGNGGGVG LAGAGGVPGA
SLGRGGGIVG IASEALASII SGRSTSPWLA RRTSPANSSG DSAIASCHEG GSTYGKEDQE
PPKSHESQEE ACHDSQPAWP HDYRPVNVKE EQVSPASSSH PRDTPKGSTQ SQVEQGAGGA
SGGGAEGPWQ PLSGSGRRKN RKNKDTVRHI TQQSERTWDR QRDRDRERDS RPGSPLPSML
AVTAWNYNGQ DIPGADVTEP NSSDSRGERL DFFLKQEETL ATESGFLGAN ESEEASGGGG
GGGISSVANL KAALMSKNSL LSLRAEMMGD DNPLLYEYLP KGGHSLSWLR SNNYCSALRP
GATGAAVHNK QGAGSSPPLP LLPPHLPPSP PPPPPPPPPP HLPSSTSAYC PPSPPTPLHL
SEPRPLEAPG LRAGATPLHS EGLDMEVEEA PEGTEPSVLP EERIKEREDM KDYSPALEGD
QSPVERDQMG EGSCAGGSSV PASVSVPGTG SKGPLALVND FTVIRKKFKC PYCSFSAMHQ
CILKRHMRSH TGERPYPCEI CGKKFTRREH MKRHTLVHSK DKKYVCKVCS RVFMSAASVG
IKHGSRRHGV CADCSGRGMA ALLDHNGETG GDISPEEELY PGDRFHDDQA ECDGDGEGEE
EMMVEGDGEI LGEGEEEAGK WKDSGMAAEA HRALDNEKEE SDSSAQEGEQ HNGSEKDFAW
IS
//
