ID A0A3B5QAA0_XIPMA Unreviewed; 563 AA.
AC A0A3B5QAA0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=TIR domain-containing adapter molecule 1-like {ECO:0000313|Ensembl:ENSXMAP00000027194.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000027194.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000027194.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000027194.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005812562.1; XM_005812505.1.
DR AlphaFoldDB; A0A3B5QAA0; -.
DR STRING; 8083.ENSXMAP00000027194; -.
DR Ensembl; ENSXMAT00000023214.1; ENSXMAP00000027194.1; ENSXMAG00000022282.1.
DR GeneID; 102229375; -.
DR KEGG; xma:102229375; -.
DR CTD; 148022; -.
DR GeneTree; ENSGT00940000163706; -.
DR InParanoid; A0A3B5QAA0; -.
DR OMA; TRHGWQD; -.
DR OrthoDB; 4640439at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.25.40.780; -; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR046946; TCAM1/2.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR040886; TRIF_N.
DR PANTHER; PTHR47230; TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1; 1.
DR PANTHER; PTHR47230:SF1; TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF17798; TRIF-NTD; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 340..472
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 563 AA; 62680 MW; CACDA5AF88A5DE56 CRC64;
MNHTELENQG TGLRAVFDIL EKAPSERLLS LTFQLGESPE DTIIHALCLI ILQREALALE
KLQMLEDNPL ANHLAEKWHS GGGKFDDFGA HCSLFEAKMG ESLSSLARVF KILSEQRLCE
PRLRNLAYKR AIFCECLNTS SLEYENFREE ARAVCGPQFT EPMCFHSDLK SESSIDPCRK
ISEGKATLNT AASLDESANV HCLPTPLQDS PSEPSYPSHL EISLPPTISY QGDKAAAESP
GNPILNPSIN ENKTENVPEQ IHCTSPQHTS TEISQFGAKK SIKIEEASMR SNESAAQPLK
PYTQTKSSLP AATHIILPSS TGLKSTHISK VDEEEDEEDI FYAFVILHAP EDSDVAESMK
EKLEAVIGIE GATFSGDFAV PGKSTLRCVE DAVNNSAFTF LLLTRNFNSQ MVEMKTNIAL
INSINNAHKF NTVIPLLPLE NCMPKEQMPI TLQTLMPLDE RKNFERKLKK AFNKAKIEKQ
RKIWVQEQRM KRMRLKEKER QRLYMEQQLV LGAAVQREQD SGDPGPQRLA HSIHIENANY
IVIGNDSTMT VGVEGSADKG GLS
//
