ID A0A3B5QJN9_XIPMA Unreviewed; 1180 AA.
AC A0A3B5QJN9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=NLR family CARD domain-containing protein 3-like {ECO:0000313|Ensembl:ENSXMAP00000030727.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000030727.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000030727.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000030727.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B5QJN9; -.
DR Ensembl; ENSXMAT00000024012.1; ENSXMAP00000030727.1; ENSXMAG00000026696.1.
DR GeneTree; ENSGT01100000263487; -.
DR InParanoid; A0A3B5QJN9; -.
DR OMA; GNGEDCW; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF14484; FISNA; 1.
DR Pfam; PF13516; LRR_6; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 2.
DR Pfam; PF17779; NOD2_WH; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM01288; FISNA; 1.
DR SMART; SM00368; LRR_RI; 4.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 351..483
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT DOMAIN 990..1180
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 150..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1180 AA; 134867 MW; BBCA7CE0D440ECBA CRC64;
MEKVTLKNKH EFRDLSFKSH DSKDMWWDFK SDQPPPPERM EKVTLKNENE SKDLSFKSHD
SKDIWWDFKS DQPPPPERME KVTLKNKHEF RNLSFKSHNS RDMWWDFKSD QPPPPERTHQ
KFQLEPELEP QPDLMSVVSE NSYDFHIDFE SSGPSSERMS QKISEIPSGP SGPPYQTQLD
SIFMLLKENI VTFVTNELKK IQKVLSPEDP EWSECERDDE EFEGENEEQR KSSREAVMKI
TMNFLRRMKQ EELVERLQRK HLTAIGQHKL KSSLKKKFHC VFEGIAKAGS PTLLNQIYTE
LYITEGGTGG VNDEHEVRQI ETASRKPHRP ETTIRQEDIF KVQPGRDQPI RTVMTKGVAG
IGKTVLTQKF TLDWAEDKAH QNIQFIFPFT FRELNVLKEK KFSLVELIHH FFTETKGICS
FEHFQVLFIF DGLDESRLPL DFHNKEILTD ATESSSVDVL LTNLIRGKLL PSALLWITTR
PAAASQIPPQ CVGMVTEVRG FTDSQKEEYF RKRFRDEQQA SRIISHMKTS RSLHIMCHIP
VFCWITATVL KDVLEIREGG KLPSTLTEMY IHFLVVQTKV KKVKYDEGSE KDPHWSPESR
KMIESLGKLA FDQLQKGNLI FYESDLTDCG IDIRAASVYS GVFTQIFREE RGLYQDKVFC
FIHLSVQEFL AALHVHLTFI NSGVNLMEEK QSAIPTLFHK SKIISLHQNA VDRALQSSNG
HLDLLLRFLL GLSLQTNQRL LKGLFTQTGS CSQSNQRLLQ GLLVQTGSSS QTNQKIVQYI
KEKINENVSA EKSINLFHCL NELNDCSLVE EIQQSLSSGS LSTDKLSPAQ WSALGFILLS
SGEDLDVFDL TKYSASEEAL LRLLPVVKAS NKALLSNCNL SERSCEALSS VLRSQSSSLK
ELDLKNNSLK DSGVKLLSDG LRSPYCKLEK LTLSGCLITE DGCASLVSAL KSNPHHLQEL
DLSYNHPGDS GVNMLSAGLR DPHWRLEMLR VEPAGNRYLK PGPWRYSCQL TFDRDTINQN
FQLSNNDRKV TDMQKAHSDT DYLDRRNIPQ LLCRNVISDR CYWEVEWRGK IEISVTYRGI
RRRGLTNDSV CAKSDDSWSL SCSDDGYTVS HYKNRKLLSS SSFSTVSNRV AVYVDCPAGS
LSFYRVSSDS LIHLHTFNTT FTDTLYPGFT VLPGSSVFLC
//
