ID A0A3B5QKV7_XIPMA Unreviewed; 562 AA.
AC A0A3B5QKV7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000032179.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000032179.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000032179.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B5QKV7; -.
DR Ensembl; ENSXMAT00000035960.1; ENSXMAP00000032179.1; ENSXMAG00000025243.1.
DR GeneTree; ENSGT01070000253760; -.
DR InParanoid; A0A3B5QKV7; -.
DR OMA; KFNITHE; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 44..178
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 562 AA; 64317 MW; BBAEBE32048ECF10 CRC64;
SQKKFAWQLH IFTPGKKFFQ NLHVSAIRCH DIFKAFPDQH GAIRVVLTNG VAGVGKTFSV
QKFTLDWADG LENQDVSVVV LFSFRELNLI RDEQHSLLTL LHVFHPTLQK LPAEQLVKCK
LLFIFDGLDE SRFSLDFNNS QLVSDVTQKS SVNVLLTNLI KGNLLPSALI WITSRPAAAN
QIPPSCVTRV TEVRGFTDTQ KEEYFRKRFS DEKLSSRIIS HVKTCRSLHI MCGIPVFCWI
TATVLENMLT SEQRGELPKT MTDMYSHFLL TRSQELMEAD REDLLKLGRL AFEHLEKGNI
MFYQEDLEQC GLDVTEASVY SGVCTEIFKR ESVIFQKPVY CFVHLSIQEF LAAVYMLHCF
TSRKSEVIRS ENGHLDLFVR FLHGLTVESN QRLLEDLLGQ TENSPETIQR IITNLKEMNT
DRISTDRRIN IFYCLVEMND VSFYQEIQRL LVSGKQLSVT DCSALAFMLQ MSEKVLDNLD
LEKYNTSPDG RLRLVPAVRN CRKARLSETS WTSLFSALKS NPTHLTELYL YRTNLGGSGV
KELCGFLQTE GCRLEKLGYV II
//
