ID A0A3B5QL63_XIPMA Unreviewed; 1233 AA.
AC A0A3B5QL63;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Deleted in malignant brain tumors 1 protein-like {ECO:0000313|Ensembl:ENSXMAP00000031708.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000031708.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000031708.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000031708.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; A0A3B5QL63; -.
DR Ensembl; ENSXMAT00000033708.1; ENSXMAP00000031708.1; ENSXMAG00000004285.2.
DR GeneTree; ENSGT00940000166622; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 9.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071:SF25; ANTIGEN WC1.1-LIKE-RELATED; 1.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 9.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 9.
DR SUPFAM; SSF56487; SRCR-like; 9.
DR PROSITE; PS00420; SRCR_1; 1.
DR PROSITE; PS50287; SRCR_2; 9.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1233
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017374872"
FT TRANSMEM 1127..1149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..125
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 128..223
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 228..328
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 331..425
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 430..530
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 533..630
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 633..733
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 738..838
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 841..941
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 1172..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 50..114
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 63..124
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 94..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 196..206
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 253..317
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 266..327
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 297..307
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 398..408
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 455..519
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 468..529
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 499..509
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 599..609
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 658..722
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 671..732
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 702..712
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 763..827
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 776..837
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 807..817
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 866..930
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 879..940
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 910..920
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1233 AA; 134593 MW; 1A426F8A7EEE2330 CRC64;
MESQHFCFLL IAGLLSLPLL IECDKIRLVG PSRCAGRVEI YHDDVWGTVC DDHWSIANAE
VVCRELNCGI VMEAKKSAFF GEGTHEIWLD DVQCNGKETS ITKCQHKPFG INNCGHSEDA
GVVCSERIRI LNGTSRCNGR VELFQGGQWK RVCSSDWGKE EADVVCREIS CGSPVVQAAT
QYFGEGQGLH GVKANCVGNE TSISSCVMQD FRETCIDATI SCMNSKPIRL INGTSRCSGR
VEVYYEGQWG TVCDDKWGMQ EAAVTCREMN CGNALAVKYK AFYGKGQDQV WLDDIDCTGD
EKSLSDCPHR GFGEHDCDHH EDAGVVCSEN VRLINGTDSC SGRVEVFYNG RWGKICSNSW
GGTEATVLCK ELSCGSPKKN QDVFTFGDSP LAGLISRCSG NVSSISQCVV DEHIGKCEGV
SIACAGNPPI RLVNGTDRCS GRVEVLHDGQ WGTVCDDEWD IRDAQVVCRA LDCGSAQTAK
TAAYFGQGQG DIWLDDMNCI GNESSLLHCY RPPFGENNCG HGEDAGVICS ANLRLINGTD
TCSGRVEIYN GGHWSSVYNV NFGMNEAAVV CRDMNCGDAV KATGSFGQSV DLRGLKMSCS
GTERSVTQCT LREYTRNRSD RIQEASVQCS GNVKLSDGPH RCAGRVEFFD KGQWGTVCGE
SWDINDATVV CRQLNCERAH KITKMTEYGL GVGQTWIEQI ECSGRESTLS QCPQRPYRDR
TCNTTAKAGV ICTGSLEVRL AKGKDECSGR VEVRHAETWQ TVCDAGWTES KAEVVCQLLE
CGHTLNAPGG ASFGQGNGTV VEASDSCFGN MTSLQKCSVN GFRRSTCGHE HDAGAVCAAQ
LRLVGGSGQC SGRVEIFYKG QWGTVCDDDW QMSNADVVCR QIGCGHAVSA PTSAHFGRGS
GPIWLDNVEC TGQEVALAHC QHRGFGENNC GHGEDAGVIC LGDLQKPQIS LSPSAEVIWG
DKVEITCTVA TEHLDFNLNG SYFCEYHKKL ADQIIYYPQG NTADISVNVK LGIPSISLTS
AHQMVIYSPV KLSITKGSEF SITCAIHSRF PGGIFYLSNY NKNISEAKPA FGHNIFYMAY
FEFPEIDFKD QGDYACVYAV NISSIPFCSS PSKTLQLTVL ATTSASVAAV VVGVLLILLV
LLVIGFFVWR KKWRGAVIMV QFNNRLEPKK QELDDRGNGA LDERERTNQL YDRGQHDSMK
RMNNNLEFES TEEKVPEDLV GRVCYESEPL VDP
//
