ID A0A3B5QUJ5_XIPMA Unreviewed; 756 AA.
AC A0A3B5QUJ5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000034934.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000034934.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000034934.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B5QUJ5; -.
DR Ensembl; ENSXMAT00000035907.1; ENSXMAP00000034934.1; ENSXMAG00000022398.1.
DR GeneTree; ENSGT01100000263487; -.
DR InParanoid; A0A3B5QUJ5; -.
DR OMA; QTWIRSH; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF14484; FISNA; 1.
DR Pfam; PF13516; LRR_6; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM01288; FISNA; 1.
DR SMART; SM00368; LRR_RI; 2.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT DOMAIN 123..254
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 756 AA; 86245 MW; BCB155E1A6DB9A85 CRC64;
EQMRRNREDF EKMVQRFLRR MNQEELANCL RLKSLITCQE TLKSNMKTKF QHVFEGIAKS
GNPTVLNEIY TELYITKGDS GEVNNEHEVR QIEAVSWKPD QPETSIRHED IFKPVSGRDE
PIKTVMTKGV AGIGKTVLTQ KFTLDWAENR VNQDIQFIFP IKFRELNLLK EQFSLVDLVH
HFFSETKGIF RFEELKIVFI FIGLDESRLA LDFHNNEILM DVTKSTSVDV LLTNLIRGNL
LPKAHLWITT RPAAASRIPP EFIGKMTEIR GFTDPQKDEY FKKRFKYKKE ARMVIYHIKK
SRTLHIMCHI PIFCWITATV VEDMLNKKDE ELPKTLTEMY IHFLVVQNKL KVIKYDGLQC
ETDSHWSPES QKMIESLGKL AFDQLMKGNL IFYESDLAEC GIDIRAASVC SGVFTQIFRE
ERSLYQNKVF CFVHLSVQEF LAALHVHLIF IKSGINLLSA VDMALESPDG HLDLFLRFLL
GLSLETNKRR LRGFVAQTEE SLAIIKDTAQ YIKEKLNHLC VEKSINLFHC LSELNDPSLM
EEIQLSLRTG SLSAHQLSPA QWSALIFMLL SSEKDLEMFD LKKYSASEDA LLGLLGCNLS
ERSCEALSSV LTCQDSRVKE LDLSNNNLGD SGVKLLCDGL KSPNCELEIL RLVHILKSDE
ARVKMCCVCS VCRLSGCLIT EEGFAALASA LMLNPSHLRE LDLSYNHPGE TGAQPLLAGL
EDAKWKLETL TQCNKSTLLA SSVTCYYTSL VKLTVH
//
