ID A0A3B5QVW4_XIPMA Unreviewed; 539 AA.
AC A0A3B5QVW4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=RNA-binding protein 47 {ECO:0000256|ARBA:ARBA00015191};
DE AltName: Full=RNA-binding motif protein 47 {ECO:0000256|ARBA:ARBA00030579};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000034556.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000034556.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000034556.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RRM RBM47 family.
CC {ECO:0000256|ARBA:ARBA00005319}.
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DR AlphaFoldDB; A0A3B5QVW4; -.
DR Ensembl; ENSXMAT00000023619.1; ENSXMAP00000034556.1; ENSXMAG00000009874.2.
DR GeneTree; ENSGT00940000156979; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd12485; RRM1_RBM47; 1.
DR CDD; cd12491; RRM2_RBM47; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR047044; RBM47_RRM1.
DR InterPro; IPR034440; RBM47_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF6; RNA-BINDING PROTEIN 47; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 86..164
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 166..248
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 261..333
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 59213 MW; EE9BA6FF95DC8949 CRC64;
MTAEDPVSSS NMSNNSTPSK PSKPSGASFH PLQGQITLPE GVAGAPNEAA LLSLMERTGY
GMVQENGQRK YGPPPGWSGP APPRGCEIFV GKIPRDVYED ELVPVFETVG RIYEMRLMMD
FDGKNRGYAF VMYTEKHEAK RAVRELNNYE VRPGRLLGVC SSVDNCRLFI GGIPKTKKRE
EILEEVSKVT EGVLDVIVYA SAADKMKNRG FAFVEYESHR AAAMARRKLM PGRIQLWGHQ
IAVDWAEPEI DVDEDVMETV KILYVRNLMM ETSEETIRNI FSQWNPGCVE RVKKIRDYAF
VHFISRDDAV LAMDHLNGTE IEGSCIEVTL AKPVDKEQYS RQKASKGGAS ATPEPTQQNY
IYQCDPYTLA YYGYPYSTLI GPNREYFVKV ALPTLGGQYQ VFSAPPAAKV MEEGKVHSVE
HLMNPLTMQH PEHSAATAAA AAATVLPSVS TPPPFQGRPI TPVYAMAHNV QRIPAAASLY
GAGYVPIANY AANTAALAAL QKNAAMAATA YGGYAGYAMP QAFPAAAFPL PIHDIYQSY
//
