ID   A0A3B5R0W6_XIPMA        Unreviewed;      1008 AA.
AC   A0A3B5R0W6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Xiphophorus.
OX   NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000037263.1, ECO:0000313|Proteomes:UP000002852};
RN   [1] {ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA   Walter R., Schartl M., Warren W.;
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX   PubMed=23542700; DOI=10.1038/ng.2604;
RA   Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA   Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA   Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA   Postlethwait J.H., Warren W.C.;
RT   "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT   evolutionary adaptation and several complex traits.";
RL   Nat. Genet. 45:567-572(2013).
RN   [3] {ECO:0000313|Ensembl:ENSXMAP00000037263.1}
RP   IDENTIFICATION.
RC   STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000037263.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B5R0W6; -.
DR   Ensembl; ENSXMAT00000025031.1; ENSXMAP00000037263.1; ENSXMAG00000028480.1.
DR   GeneTree; ENSGT01100000263487; -.
DR   OMA; DSLRMDH; -.
DR   Proteomes; UP000002852; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 4.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002852}.
FT   DOMAIN          193..325
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          817..1008
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          31..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1008 AA;  113944 MW;  86C8D5A4A34608B9 CRC64;
     MLCFSALWNF NVKLLVFPSV NTKELKKIQK VLSPNDPEHS ESQRDDEGLE GDDEEQRRSN
     REAVMKITLN FLRRMKQEEL ADHLQSTMIF FISDFCYCVN LGYFAPVCQH QLKSGLKKKF
     QSVFEGIAKA GSPTLLNQIY TELYITEGGT GEVNDEHEVR QIETASRKPD RPETTIRQED
     IFKVQPGRDP PIRTVMTKGV AGIGKTVLTQ KFTLDWAEDK AHQKIQFIFP FTFRELNVLK
     EKKFSLVELV HHFFSETKEI CSFEHFQVLF IFDGLDESRL PLDFHNKEIL TDATESTSVD
     VLLTNLIRGN LLPSALLWTT TRPAAANQIP PQCVGMVTEV RGFNDPQKEE YFRKRFRDKQ
     QASRIISHMK TSRSLHIMCH IPVFCWITAT VLEDVLETRQ GGELPRTLTE IYIHFLVVQT
     KVKKVKYDGG AETDPHWSPE SRKMIKSLGK LAFDQLQKGN LIFYESDLTE CGIDIRAASV
     YSGVFTQIFK EERGLYQDKV FCFVHLSVQE FLAALHVHLT FINSGSDVMK ETQRSKKSSL
     LNKSDLKSLH QRAVDQALQS PNGHLDLFLR FLLGLSLQTN QRLLKGLLKQ TGSSSQTNQE
     TVQYIKEKIS ENVSAEKSIN LFHCLNELND RSLVEEIQQS LSSGSLSTDK LSPAQWSALI
     FILVSSGKDL DVFDLKKYSA SEEVLLRLLP VVKASNKVLL SGCNLSERSC EALSSVLSSQ
     SSSLRELDLS NNNLRDSGVK LLSAGLKSPN CNLETLSLSG CLVSEEGCAS LASALTSNPS
     HLKELDLSYN HPGDSGVKLL SAGLKDPHWR LEALRYGGTC CRIPFLTPGL RKYSCQLTID
     TNTVNRKLKL SEDNRKVTHV EELQSYPDHP DRFDSYPQLL CRTGLTGRCY WEVEWRGGVY
     ISVSCRRIRR KGDSADCVFG YNVHSWSLSC SDDVGYSVWH NNIKTRLSSS SVSNRVAVYV
     DCPAGILSFY RVSSDSLILL HTFNTTFTEP LIPGFRFWFS SGSSVFLC
//