ID A0A3B5R2X4_XIPMA Unreviewed; 743 AA.
AC A0A3B5R2X4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Spermatid perinuclear RNA-binding protein {ECO:0000256|ARBA:ARBA00022368};
GN Name=STRBP {ECO:0000313|Ensembl:ENSXMAP00000036691.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000036691.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000036691.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000036691.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 8083.ENSXMAP00000036691; -.
DR Ensembl; ENSXMAT00000028459.1; ENSXMAP00000039686.1; ENSXMAG00000001700.2.
DR Ensembl; ENSXMAT00000041591.1; ENSXMAP00000036691.1; ENSXMAG00000001700.2.
DR GeneTree; ENSGT00940000154687; -.
DR OMA; APLKGWX; -.
DR OrthoDB; 4565640at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd19909; DSRM_STRBP_rpt1; 1.
DR CDD; cd19911; DSRM_STRBP_rpt2; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR044472; STRBP_DSRM_1.
DR PANTHER; PTHR45762:SF1; SPERMATID PERINUCLEAR RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 5..422
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 449..515
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 570..636
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 49..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..83
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..216
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 80711 MW; E939E9BC419E774D CRC64;
MRSFRSFSND DRHVMAKHST IYPSSQELEA VQTLVSTVEC ALKQVADWME QSSGDAPNSN
FDSQPADSTE EDDPGEEPRE EAEESNEGYS RESGGGGMLC GVMRVGLVAK GLLIKGDMDL
ELVLMCRDKP TQTLLDTVCH NLPTQIQKLT EEKYEVSSSL PEAAILVQTT TDPKLKLKIT
LTSPAMRDDE DLEEEEEEEE GQGEEEELEN GEDGEEVVEL AEAEVVEEEQ EQENGEVLGA
AAHTVEAEEE GEVLDRHRCL LALAALRHAK WFQARVNGLK SCVIVLRILR DMCNRHPIWE
PLKGWPLELI CEKAIATCNR PLGAGEALRR VMECLASGIL LPGGPGLHDP CEKEPTDTLA
DMTDQEAEAI TYGAQHALRL MAFGQIYKVL EMEPLPSNKP SQKYPWSDKE GLGLKRPYED
GTMDDKDLIK KMKRNLRKVL DSKAIDSNQP MNALMRLNQI RPGLQYRLLS QSGPVHAPVF
TMSVDVDGTV YEASGSSKKT AKLHVAVKVL QAMGYPTGFD SDLDPMSSDE KSDSEGKSET
SSHSSNNPTH SSDGSNTLEV RTQGPILTAS GKNPVMELNE KRRGLKYELI SESGGSHDKR
FVMEVEVDGQ KFRGAGPNKK VAKASAALAA LEKLFSGPNA AANKKKKILP PTKGALAAAA
AASAVAAQVA RGRGRAALAR GAFVSAAAPG YVTPGFGTPY GYSPAAAAAP AYGGLFIDNP
FYQPRTIAPF IIHLGPQDLF SDF
//
