ID A0A3B5R521_XIPMA Unreviewed; 433 AA.
AC A0A3B5R521;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transmembrane protein 200C-like {ECO:0000313|Ensembl:ENSXMAP00000038339.1};
GN Name=TMEM200C {ECO:0000313|Ensembl:ENSXMAP00000038339.1};
OS Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Xiphophorus.
OX NCBI_TaxID=8083 {ECO:0000313|Ensembl:ENSXMAP00000038339.1, ECO:0000313|Proteomes:UP000002852};
RN [1] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RA Walter R., Schartl M., Warren W.;
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP 163 A {ECO:0000313|Proteomes:UP000002852};
RX PubMed=23542700; DOI=10.1038/ng.2604;
RA Schartl M., Walter R.B., Shen Y., Garcia T., Catchen J., Amores A.,
RA Braasch I., Chalopin D., Volff J.N., Lesch K.P., Bisazza A., Minx P.,
RA Hillier L., Wilson R.K., Fuerstenberg S., Boore J., Searle S.,
RA Postlethwait J.H., Warren W.C.;
RT "The genome of the platyfish, Xiphophorus maculatus, provides insights into
RT evolutionary adaptation and several complex traits.";
RL Nat. Genet. 45:567-572(2013).
RN [3] {ECO:0000313|Ensembl:ENSXMAP00000038339.1}
RP IDENTIFICATION.
RC STRAIN=JP 163 A {ECO:0000313|Ensembl:ENSXMAP00000038339.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM200 family.
CC {ECO:0000256|ARBA:ARBA00005308}.
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DR RefSeq; XP_005814778.1; XM_005814721.1.
DR AlphaFoldDB; A0A3B5R521; -.
DR Ensembl; ENSXMAT00000023870.1; ENSXMAP00000038339.1; ENSXMAG00000023390.1.
DR GeneID; 102233192; -.
DR KEGG; xma:102233192; -.
DR CTD; 100003113; -.
DR GeneTree; ENSGT00530000063698; -.
DR InParanoid; A0A3B5R521; -.
DR OMA; CCSANPP; -.
DR OrthoDB; 5309875at2759; -.
DR Proteomes; UP000002852; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018787; DUF2371_TMEM200.
DR PANTHER; PTHR31815; AGAP005329-PA; 1.
DR PANTHER; PTHR31815:SF2; TRANSMEMBRANE PROTEIN 200C; 1.
DR Pfam; PF10177; DUF2371; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002852};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 14..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..37
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 47103 MW; 4FBA3D2228096C5E CRC64;
MIATGGLLRI NARRQDSLRS KPHRSHPHKK KSKNKRRSEV VVVKGKLKLC SISGLVAVLG
ILVLMVGVLM AALGYWPRDG LFFSSQPREG ATMALMSFSS PAPALVEDQE PGWAESDGGD
GTNGRGNGFN QSEAVNGTSQ DVPKGFLEDF LDRYLYSDRL KVFGPLIMGI GIFLFICANA
VLHENRDKKT KVINLRDIYS TVIDLHSVRK PHPSSSGSAH QPLTNPLNGL INYVQAKSLD
SKSQMCPAAL LSRQPASSRS CSDGGGGGVF SVCQEHPPAP PPSSSNRHSL PLTSDPCWTS
HHKDTRSSFT LPRPRQRSPG ARRRHSFWAR SSGQEEQKEE EMQPPPLCAS TPPPHQFSEA
LLLLSSSSLS SLSHLLSSSS TPAPPCRRRS LPTAAFNAAY CKLTQGEDES FEWSSSHKVT
PEEAARPSQP ETP
//
