ID   A0A3B5XTK8_WHEAT        Unreviewed;       958 AA.
AC   A0A3B5XTK8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=RGH1 {ECO:0008006|Google:ProtNLM};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G026400.1};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G026400.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS1A02G026400.1};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G026400.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; A0A3B5XTK8; -.
DR   STRING; 4565.A0A3B5XTK8; -.
DR   PaxDb; 4565-Traes_1AS_13532D7C4-2; -.
DR   EnsemblPlants; TraesCS1A02G026400.1; TraesCS1A02G026400.1; TraesCS1A02G026400.
DR   Gramene; TraesCLE_scaffold_173588_01G000100.1; TraesCLE_scaffold_173588_01G000100.1; TraesCLE_scaffold_173588_01G000100.
DR   Gramene; TraesCS1A02G026400.1; TraesCS1A02G026400.1; TraesCS1A02G026400.
DR   Gramene; TraesCS1A03G0061000.1; TraesCS1A03G0061000.1.CDS; TraesCS1A03G0061000.
DR   OMA; HDNISAY; -.
DR   OrthoDB; 2909504at2759; -.
DR   Proteomes; UP000019116; Chromosome 1A.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          8..91
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          192..424
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   958 AA;  108185 MW;  479C531A16D8BC06 CRC64;
     MDIVTSAIAK LIPKLADLLV GEYKLHKNVK KNIEDLLKEL ESMNVALIKI GEVPRDQLDK
     QDKLWADDVR ELSYVIEDVV DKFLVRVDHI QPDDATNKFK GLMKRTTKLL KKVKDKYGIA
     HAIKDIQEQL QKVAARRDRN KVVVPNPTEP ITIDPCLRAL YAEATELVGI YGKRDEELMR
     LLSMEGDDAS KNRLKKVSIV GFGGLGKTTL ARAVYEKIKG DFDCRAFVPV GQNPDMKKVL
     RDILIDLSDG NPQSDLSILD VNHLIKKLHQ FLENKRYLVI IDDIWDEKLW EHINFAFSNR
     NNLGSRLITT TRIVSVSNSC CSLDHDSVYQ MEPLSVDDSR RLFYKRIFPF ESGCPNEFEQ
     VSTDILKKCG GVPLAIITIA SALAGGQKVK PKCEWDVLLQ SLGSGLTEDN SLEEMRRILS
     FSYYNLPSHL KTCLLYLCIY PEDSTIDRDG LIWKWVAEGF VHHGDQGTSL FLVGLNYFNQ
     LINRSMIQPI YDPLGQVYAC RVHDMVLDLI CNLSHEAKFV NLLDGTGNHI MSSQSNIRRL
     SLQNKNEDHQ AKPLTNIMSM SQVRSITIFP PAVSIMPSLS MFEVLRVLDL SHCNLGESSS
     LQLNLKGVGH LIHLRYLGLS GTKISKLPAE IGNLQFLEVL DLGNNDKLDE LPSTVCNLRR
     LIYLNVFSSK VVPTPGVLQN LTSIEVLRGV LVSLNIIAQE LGKLARLREL QICIKDGSLD
     LYECFVKSLC NLDHIESLYI RCNSEETSFE LMDLLGECWV PPVHLRKFVS STPTQLYALQ
     GWIKRDPSHL SNLSELIFYS VKEVQQEDVE IIGGLLSLRR LCIRSTHQTQ RLLVIRADGF
     RCMVDFYLNC GSAAQIKFEP GALPRAEEVT FSLGVRVAKE DGNCGFDLGL QGNLLSLRRP
     VMVWMYCGGA RVGEAKEAEA AVRRALEAHP NHPRIYIDMW PRIAEDAHDD DLCEDEEN
//