ID A0A3B5XUS1_WHEAT Unreviewed; 839 AA.
AC A0A3B5XUS1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0008006|Google:ProtNLM};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G065700.4};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G065700.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1A02G065700.4};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G065700.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR AlphaFoldDB; A0A3B5XUS1; -.
DR EnsemblPlants; TraesCS1A02G065700.4; TraesCS1A02G065700.4; TraesCS1A02G065700.
DR Gramene; TraesCS1A02G065700.4; TraesCS1A02G065700.4; TraesCS1A02G065700.
DR Gramene; TraesCS1A03G0162100.6; TraesCS1A03G0162100.6.CDS; TraesCS1A03G0162100.
DR OMA; NSNEMHG; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000019116; Chromosome 1A.
DR GO; GO:0019789; F:SUMO transferase activity; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR CDD; cd16792; SP-RING_Siz-like; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR031141; SIZ1/2_SP-RING.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF4; E3 SUMO-PROTEIN LIGASE SIZ1; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 12..46
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 352..433
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 86..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 839 AA; 93459 MW; 9F02836E0404E983 CRC64;
MADLASSCKD KLAYFRIKEL KDILHQLGLP KQGKKQDLID RVLALLSDEQ GQRHHGWGRK
NSFTKEAVAK IVDDIYRKMQ IQSAPDLATR SHTGSDLFRP KDEVNDSFQP QPVSKVRCIC
DSKLLNDNMI QCEDDRCHVW QHMSCVLVPD KPTEGVGPEV PPHFYCELCR LSRADPFWVT
TGNPLPPLKF MSSGVANDGT SVLQTVEKTF QLSRADRETV QRSEYDLQVW CILMNDKVQF
RMQWPQYAEL EVNGFAVRVV TRPGSQLLGI NGRDDGPLIT TCSREGTNKI CLRRVDNRTF
CFGVRVAKRR SVPQVLNLVP KEAEGESFED ALTRVRRCLG GGDTAENADS DSDLEVVTES
VTVNLRCPNS GSRMKTAGRF KPCIHMGCFD LDTFVELNQR SRKWQCPICL KNYSLENLMI
DPYFNRITSL LRDCSEDVNE IDIKPDGSWR VKGDVPTREL SQWHMPDGTL CISKEDNKPG
VENFNELKIE GTSDGHKSLK IGIKRKNGIW EVSNKADDKK PSVVGNITQN NITFRTPNTF
PMSSSPTGSY RDGEDTSVNQ EGSMHIDLSL NNGHEFESFP LNFRQTYNTE DTSQQLSAGD
VIVLSDSDEE NDTIVCPPTV YDNTTANDSG FPFATSGAGF TGRYQEDAGV GTSGLGLLSN
NADDFEMTNW QMPYSQPEQG YQFFGDGTAD TYVGSHNSFS ITPNDYSLDC NVGIEEASVA
HDLPVYRSNN EMHGSLVDNP LAFGGDDPSL QLFLPTGGGG NEEPATANGL NLQEQIRSNE
TGVEPLIDAA SVLPSTNNDR DDGANLNPRR IDHIFSHPRQ PRSRSVRPRL CLSIDSDSE
//
