ID A0A3B5Y246_WHEAT Unreviewed; 426 AA.
AC A0A3B5Y246;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=S-acyltransferase {ECO:0000256|RuleBase:RU079119};
DE EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119};
DE AltName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G272200.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G272200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1A02G272200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G272200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-
CC hexadecanoyl-L-cysteinyl-[protein]; Xref=Rhea:RHEA:36683, Rhea:RHEA-
CC COMP:10131, Rhea:RHEA-COMP:11032, ChEBI:CHEBI:29950,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57379, ChEBI:CHEBI:74151;
CC EC=2.3.1.225; Evidence={ECO:0000256|RuleBase:RU079119};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- DOMAIN: The DHHC domain is required for palmitoyltransferase activity.
CC {ECO:0000256|RuleBase:RU079119}.
CC -!- SIMILARITY: Belongs to the DHHC palmitoyltransferase family.
CC {ECO:0000256|ARBA:ARBA00008574, ECO:0000256|RuleBase:RU079119}.
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DR AlphaFoldDB; A0A3B5Y246; -.
DR SMR; A0A3B5Y246; -.
DR STRING; 4565.A0A3B5Y246; -.
DR PaxDb; 4565-Traes_1AL_2EC583AC9-1; -.
DR EnsemblPlants; TraesCS1A02G272200.1; TraesCS1A02G272200.1; TraesCS1A02G272200.
DR Gramene; TraesCAD_scaffold_042697_01G000200.1; TraesCAD_scaffold_042697_01G000200.1; TraesCAD_scaffold_042697_01G000200.
DR Gramene; TraesCLE_scaffold_034250_01G000200.1; TraesCLE_scaffold_034250_01G000200.1; TraesCLE_scaffold_034250_01G000200.
DR Gramene; TraesCS1A02G272200.1; TraesCS1A02G272200.1; TraesCS1A02G272200.
DR Gramene; TraesCS1A03G0687700.1; TraesCS1A03G0687700.1.CDS; TraesCS1A03G0687700.
DR Gramene; TraesKAR1A01G0291940.1; cds.TraesKAR1A01G0291940.1; TraesKAR1A01G0291940.
DR Gramene; TraesPAR_scaffold_022757_01G000200.1; TraesPAR_scaffold_022757_01G000200.1; TraesPAR_scaffold_022757_01G000200.
DR Gramene; TraesROB_scaffold_029247_01G000200.1; TraesROB_scaffold_029247_01G000200.1; TraesROB_scaffold_029247_01G000200.
DR Gramene; TraesWEE_scaffold_041563_01G000200.1; TraesWEE_scaffold_041563_01G000200.1; TraesWEE_scaffold_041563_01G000200.
DR OMA; MDDHHGT; -.
DR OrthoDB; 276762at2759; -.
DR Proteomes; UP000019116; Chromosome 1A.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IBA:GO_Central.
DR GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR InterPro; IPR001594; Palmitoyltrfase_DHHC.
DR PANTHER; PTHR22883:SF482; PROTEIN S-ACYLTRANSFERASE 9-RELATED; 1.
DR PANTHER; PTHR22883; ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF01529; DHHC; 1.
DR PROSITE; PS50216; DHHC; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU079119}; Membrane {ECO:0000256|RuleBase:RU079119};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|RuleBase:RU079119};
KW Transmembrane {ECO:0000256|RuleBase:RU079119};
KW Transmembrane helix {ECO:0000256|RuleBase:RU079119}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 181..204
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT DOMAIN 136..261
FT /note="Palmitoyltransferase DHHC"
FT /evidence="ECO:0000259|Pfam:PF01529"
FT REGION 347..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 47716 MW; B596C11630893ACB CRC64;
MAQPQQRVYQ AWKGNNRFFL GGRLIFGPDA KSLLVSVALI VVPVLVFCAF IAPHLLHRFS
GYNAGYAIPA VAVGFMIYVL LLLLITSAQD PGIVPRASHP PEEDFAYGNP LAGETPGRLQ
FPRIKEVMVN GMLVKIKYCD TCMIYRPPRC SHCSICNNCV ERFDHHCPWV GQCIGQRNYR
YFFLFVSSST LLCIYVFAMS ALHIKFLMDG DYPTVWKAFK HSPACLVLMI YCFIALWFVG
GLTGFHSYLI STNQTTYENF RYRADSRPNV YDRGCLNNFL EVLCSKGKPS KHRFRAYVQE
EVRAPVVNFG RQMEEEPAGG PRAKVEDDLE IGSDLLKISR RRNYEDVDVE MGNQDDGETE
GTGGPKLAAG SGSQIPAVGS EVRVRHSSWD RRSGNWDMSS DMIGRSASDV LGRSASLTEA
GPRSQR
//
